Journal :   Asian Journal of Research in Chemistry

Volume No. :   5

Issue No. :  8

Year :  2012

Pages :   1084-1091

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Oxadiazole: A Promising Class with Different Pharmacological Activity

Address:   Tukaram M. Kalyankar1*, Rajendra B. Kakade,2 Praveen B. Harshe1.
1School of Pharmacy, S R T M University, Nanded-431606, India 1* 2University Dept. of Pharmaceutical Sciences, Rashtrasant Tukadoji Maharaj Nagpur University, Campus, Nagpur 440033,
*Corresponding Author

Oxadiazoles are the class of five membered heterocyclic ring structures which is the flexible lead structure for new important biological activity. This has the important place to synthesis of class of different pharmacological activities. Among a wide variety of heterocyclic that have been explored for developing pharmaceutically important molecules, oxadiazole have played important role in Medicinal Chemistry. Moreover, oxadiazoles have acquired a special place in heterocyclic field because of their diversified activities such as antimicrobial, anti-inflammatory, antitubercular, anticancer, anticonvulsant properties. A brief review of the literature available on the correlation between the chemical structure and the biological activity of 1,3,4-oxadiazoles.
1,3,4-oxadiazole, 2,5-disubstituted-1,3,4-oxadiazole, Pharmacological activity.
Tukaram M. Kalyankar, Rajendra B. Kakade, Praveen B. Harshe. Oxadiazole: A Promising Class with Different Pharmacological Activity. Asian J. Research Chem. 5(8): August, 2012; Page 1084-1091.
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