Journal :   Asian Journal of Research in Chemistry

Volume No. :   6

Issue No. :  1

Year :  2013

Pages :   68-70

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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In Vitro Antihelmintic Activity and Preliminary Phytochemical Screening of Whole Plant of Vernonia cinerea



Address:   S. Ushasri*, K. Nagaraju, D. Prasanthi, K. Ramadevi, CH. Sudha Bhargavi
Sri Siddahartha Pharmacy College, Ammavarithotha, Nuzvid, India-521201
*Corresponding Author
DOI No:

ABSTRACT:
Vernonia cinerea (Asteraceae) is a potential medicinal plant and as it is a non cultivated plant it is widely distributed in waste lands and open forests in India. The alcoholic, etheral and chloroform extracts were obtained from the roots of plant Vernonia cinerea by soxhlet extraction or continuous hot percolation methods and the extracts were evaluated for their respective antihelmintic activity, against locally available earth worms (Pheretima posthuma). Three concentrations (10, 30, 60 mg/ml) were prepared from each extract and were used for the study over earth worms. The study involves the determination of time of paralysis and time for death of the earth worms tested. The results obtained from the study revealed the fact that chloroform and alcoholic extracts from the roots of Vernonia cinerea possess significant antihelmintic effect. A solution of Albendazole was prepared in same concentration as that of the extract and was used as standard. A 2% tween-80 suspension prepared using normal saline solution was used as control or blank.
KEYWORDS:
Vernonia cinerea, Pheretima posthuma, antihelmintic activity, 2% tween-80 suspension, Albendazole.
Cite:
S. Ushasri, K. Nagaraju, D. Prasanthi, K. Ramadevi, CH. Sudha Bhargavi. In Vitro Antihelmintic Activity and Preliminary Phytochemical Screening of Whole Plant of Vernonia cinerea. Asian J. Research Chem. 6(1): January 2013; Page 68-70.
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