Journal :   Asian Journal of Research in Chemistry

Volume No. :   6

Issue No. :  10

Year :  2013

Pages :   973-976

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Development and Validation of Multi-Component Mode UV Spectrophotometric Method for the Estimation of Telmisartan and Amlodipine besylate in Combined Dosage Form



Address:   Shishir Maheshwari*, Atul Srivastav
Department of Pharmaceutical Chemistry, IIMT College of Medical Sciences, Meerut-250001
*Corresponding Author
DOI No:

ABSTRACT:
A simple, sensitive, precise and specific UV spectrophotometric method for Multicomponent Mode of Amlodipine besylate and Telmisartan in combine dosage form has been developed. The wavelengths 238 nm and 295 nm were selected for estimation of Amlodipine besylate and Telmisartan respectively, where Methanol was used as solvent. Linearity were observed in the concentration range of 2-30 µg/ml (r2=0.9999) and 2-25 µg/ml (r2=0.9994) for Amlodipine besylate and Telmisartan. These methods were validated according to ICH guidelines.
KEYWORDS:
Telmisartan, Amlodipine besylate, Multi Component Mode method.
Cite:
Shishir Maheshwari, Atul Srivastav. Development and Validation of Multi-Component Mode UV Spectrophotometric Method for the Estimation of Telmisartan and Amlodipine besylate in Combined Dosage Form. Asian J. Research Chem. 6(10): October 2013; Page 973-976.
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