Journal :   Asian Journal of Research in Chemistry

Volume No. :   6

Issue No. :  3

Year :  2013

Pages :   272-277

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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A Review on 1,3,4-Thiadiazoles



Address:   Y. Pradeep Kumar*, Dr. M. Sreenivasulu, R. Yasmeen, V. Ramya Smruthiraj , V. Swathi
Dept. Of Pharmaceutical Chemistry, Annamacharya College of Pharmacy, New Boyanapalli, Rajampet, Kadapa, 516150
*Corresponding Author
DOI No:

ABSTRACT:
Heterocyclic compounds occupy a central position among those molecule that makes life possible. The chemistry of heterocyclic compounds has been an interesting field of study for a long time. Heterocyclic nucleus 1,3,4-thiadiazole constitutes constituents an important class of compounds for new drug development. The synthesis of novel thiadiazole derivatives and investigation of their chemical and biological behavior have gained more importance in recent decades. During the recent years there has been intense investigation of different classes of thiadiazole compounds, many of which possess extensive pharmacological activities. Among of these compounds having1,3,4,-thiadiazole nucleus are known to exhibit unique Antioxidant/radio protective activity, In vitro inhibition of cyclo oxygenase and 5-lipoxygenase activities, Molluscicidal activity, Carbonic anahydrase inhibitors, Anti-cancer activity, Anti convulsant activity ,Antifungal activity, Anti bacterial activity, Anti cholinergic activity, Anti histaminic activity, Anti-depressant activity, Anti-tuberculosis activity The present review highlights the recently synthesized thiadiazole possessing important biological activities.
KEYWORDS:
1,3,4-thiadiazoles, anti fungal activity, Molluscicidal activity, Carbonic anahydrase inhibitors, Anti-cancer activity, Anti convulsant activity.
Cite:
Y. Pradeep Kumar, M. Sreenivasulu, R. Yasmeen, V. Ramya Smruthiraj , V. Swathi. A Review on 1,3,4-Thiadiazoles. Asian J. Research Chem. 6(3): March 2013; Page 272-277.
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