Journal :   Asian Journal of Research in Chemistry

Volume No. :   6

Issue No. :  4

Year :  2013

Pages :   403-406

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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UV Spectrophotometric Method Development and Validation for Estimation of Doxycycline Hydrochloride in Bulk and Capsule Dosage Form



Address:   Singh Kumar Rakesh1*, Patel Singh Pankaj1, Sharma V. K.1, Roy R. K.2
1KNGD Modi Institute of Pharmaceutical Education and Research, Modinagar, U. P.-201204
2Dr. K. N. Modi Institute of Pharmaceutical Education and Research, Modinagar, U. P.-201204
*Corresponding Author
DOI No:

ABSTRACT:
A novel, simple, sensitive and rapid UV Spectrophotometric method was developed for the estimation of Doxycycline hydrochloride in bulk and its pharmaceutical capsule dosage forms. Doxycycline hydrochloride exhibited maximum absorbance at 271 nm in distilled water and obeyed linearity in the concentration range of 5-35 ppm. The proposed method has been applied successfully for the analysis of Doxycycline hydrochloride either in bulk or pharmaceutical capsule dosage forms with good accuracy and precision. The method herein described can be employed for quality control and routine analysis of Doxycycline hydrochloride in pharmaceutical capsule dosage forms.
KEYWORDS:
Doxycycline hydrochloride, UV Spectrophotometry, maximum absorbance, bulk, capsule.
Cite:
Singh Kumar Rakesh, Patel Singh Pankaj, Sharma V. K., Roy R. K.. UV Spectrophotometric Method Development and Validation for Estimation of Doxycycline Hydrochloride in Bulk and Capsule Dosage Form. Asian J. Research Chem. 6(4): April 2013; Page 403-406.
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