Journal :   Asian Journal of Research in Chemistry

Volume No. :   6

Issue No. :  6

Year :  2013

Pages :   618-622

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Synthesis, Anti-bacterial, Anti-fungal and Anti-inflammatory Activities of Some Novel 3, 5-Diaryl-1-Aryl Pyrazoline Derivatives



Address:   M. D. Bhanushali1*, S. M. Hipparagi2
1Research Scholar, Bhagwant University, Ajmer and Department of Pharmaceutical Chemistry, Maratha Mandal’s College of Pharmacy, Belgaum. 590 016.
2 Department of Pharmaceutical Chemistry, KLE University’s, College of Pharmacy, Rajajinagar, Bangalore-40.
*Corresponding Author
DOI No:

ABSTRACT:
4-substituted acetanilide on treatment with substituted benzaldehyde affords the corresponding chalcones (C13-C24). Further treatment of chalcones with phenylhydrazine undergone cyclocondensation and gave a new series of novel 3, 5-Diaryl-1-aryl-2- pyrazoline (P13-P24). All synthesized compounds were screened for their antibacterial and antifungal activity at 75µg concentration and anti-inflammatory activity at 200mg/ kg body weight. Some of the compounds have shown excellent activity.
KEYWORDS:
Pyrazoline, Antibacterial, Antifungal, Anti-tubercular activity.
Cite:
M. D. Bhanushali, S. M. Hipparagi. Synthesis, Anti-bacterial, Anti-fungal and Anti-inflammatory Activities of Some Novel 3, 5-Diaryl-1-Aryl Pyrazoline Derivatives. Asian J. Research Chem. 6(7): July 2013; Page 618-622.
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