Journal :   Asian Journal of Research in Chemistry

Volume No. :   6

Issue No. :  6

Year :  2013

Pages :   525-530

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Synthesis and Characterization of Biologically Active Mixed Ligand complexes of 8-Hydroxyquinoline and Salicylaldehyde



Address:   Dnyaneshwar S. Wankhede1*, P. A. Kulkarni2, Nikhil S. Jadhav1, Manisha D. Gurle1, Pradip B. Wagh1, and Omkar Shankarrao3
1School of Chemical Sciences, Swami Ramanand Teerth Marathwada University, Nanded-431606, Maharashtra State, India.
2Yeshwant Mahavidyalaya, Nanded-431605, Maharashtra State, India.
3School of Life Sciences, Swami Ramanand Teerth Marathwada University, Nanded-431606, Maharashtra State, India.
*Corresponding Author
DOI No:

ABSTRACT:
In this communication the synthesis of mixed ligand transition metal complexes of Fe(III), Co(II), Ni(II), Cu(II) and Zn(II) with 8-hydroxyquinoline as a primary ligand and salicylaldehyde as a secondary ligand is reported. The synthesized complexes were characterized using instrumental techniques IR, UV, Magnetic measurements and conductivity measurements in DMSO. All complexes show very low conductance values indicating their non electrolytic nature and they have an octahedral geometry. These complexes have been screened in vitro for their antimicrobial activity. In the present series of mixed ligand metal complexes, the Cu(II) Complex (C17H13Cl2CuNO3) and Zn(II) Complex (C17H13Cl2ZnNO3) showed good antibacterial as well as antifungal activity.
KEYWORDS:
Mixed ligand complex, 8-hydroxyquinoline, Salicylaldehyde, antimicrobial activity.
Cite:
Dnyaneshwar S. Wankhede, P. A. Kulkarni, Nikhil S. Jadhav, Manisha D. Gurle, Pradip B. Wagh, Omkar Shankarrao. Synthesis and Characterization of Biologically Active Mixed Ligand complexes of 8-Hydroxyquinoline and Salicylaldehyde. Asian J. Research Chem. 6(6): June 2013; Page 525-530.
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