Journal :   Asian Journal of Research in Chemistry

Volume No. :   6

Issue No. :  7

Year :  2013

Pages :   687-689

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Synthesis, Characterization and Antimicrobial Activity of Novel Chalcones from 1-[4-(1H-imidazol-1-yl) Phenyl] Ethanone



Address:   Gondu Eswara Rao1*, S.A. Rahaman2, A. Prameela Rani3, Ch. M.M. Prasada Rao4
1Assistant Professor, NRI College of Pharmacy, Pothavarapadu Village, Agirapalli (M) A.P.
2Professor, Nirmala College of Pharmacy, Atmakur Village, Mangalagiri Mandal, Guntur Dt, A.P - 522 503
3Principal & Professor, ANU College of Pharmaceutical Science, Nagarjuna Nagar, Acharya Nagarjuna University, Guntur-530 003, (A.P), India.
4Assistant Professor, QIS College of Pharmacy, Vengamukkala Palem, Ongole, A.P-523272.
*Corresponding Author
DOI No:

ABSTRACT:
Chalcones were synthesized by condensing 1-[4-(1H-imidazol-1-yl) phenyl] ethanone with aromatic aldehydes derivatives in dilute ethanolic sodium hydroxide solution at room temperature according to Claisen-Schmidt condensation. All these compounds were characterized by means of their IR, 1H NMR spectroscopic data and microanalyses. The antimicrobial activity of these compounds was evaluated by the cup plate method.
KEYWORDS:
Chalcones, Synthesis, Antimicrobial activity.
Cite:
Gondu Eswara Rao, S.A. Rahaman, A. Prameela Rani, Ch. M.M. Prasada Rao. Synthesis, Characterization and Antimicrobial Activity of Novel Chalcones from 1-[4-(1H-imidazol-1-yl) Phenyl] Ethanone. Asian J. Research Chem. 6(7): July 2013; Page 687-689.
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