Journal :   Asian Journal of Research in Chemistry

Volume No. :   6

Issue No. :  8

Year :  2013

Pages :   765-768

ISSN Print :  0974-4169

ISSN Online :  0974-4150


Registration

Allready Registrered
Click to Login

Development and Validation of Simultaneous Equation UV-Spectrophotometric Method for the Estimation of Telmisartan and Amlodipine besylate in Combined Dosage Form



Address:   Shishir Maheshwari1*, Preeti Tiwari2, Atul srivastav1
1Department of Pharmaceutical Chemistry, IIMT College of Medical Sciences, Meerut-250001
2HOD, Department of Pharmaceutical Chemistry, IIMT College of Medical Sciences, Meerut
*Corresponding Author
DOI No:

ABSTRACT:
A simple, sensitive, precise and specific UV spectrophotometric method for simultaneous estimation of Telmisartan and Amlodipine besylate in combine dosage form has been developed. The wavelengths 238 nm and 295 nm were selected for estimation of Amlodipine besylate and Telmisartan respectively, where Methanol was used as solvent. Linearity were observed in the concentration range of 2-25 µg/ml (r2=0.9994) and 2-30 µg/ml (r2=0.9999) for Telmisartan and Amlodipine besylate respectively. These methods were validated according to ICH guidelines.
KEYWORDS:
Telmisartan, Amlodipine besylate, Simultaneous equation method.
Cite:
Shishir Maheshwari, Preeti Tiwari, Atul srivastav. Development and Validation of Simultaneous Equation UV-Spectrophotometric Method for the Estimation of Telmisartan and Amlodipine besylate in Combined Dosage Form. Asian J. Research Chem. 6(8): August 2013; Page 765-768.
[View HTML]      [View PDF]



Visitor's No. :   120022