Journal :   Asian Journal of Research in Chemistry

Volume No. :   6

Issue No. :  9

Year :  2013

Pages :   863-867

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Demethylation of Mitragynine Picrate with BBr3 and C12H25-SH /NaOMe: A new entry for Ester Derivatives Preparation based on Position Carbon 9



Address:   T.B. Goh*, M.M. Mordi, S.M. Mansor
Centre for Drug Research, Universiti Sains Malaysia, Penang 11800, Malaysia
*Corresponding Author
DOI No:

ABSTRACT:
An efficient and simple one pot method for the conversion of mitragynine picrate to 9-hydroxycorynantheidine picrate was investigated for yields, selectivity and conversion in comparisons with the CYP2D6 enzyme. By applying this particular version of procedure, preparation of various ester derivatives based on position carbon 9 will be investigated.
KEYWORDS:
Mitragynine picrate, 9-hydroxycorynantheidine, yields, conversion, selectivity.
Cite:
T.B. Goh, M.M. Mordi, S.M. Mansor. Demethylation of Mitragynine Picrate with BBr3 and C12H25-SH /NaOMe: A new entry for Ester Derivatives Preparation based on Position Carbon 9. Asian J. Research Chem. 6(9): September 2013; Page 863-867.
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