Journal :   Asian Journal of Research in Chemistry

Volume No. :   7

Issue No. :  1

Year :  2014

Pages :   55-57

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Analytical Method Development and Validation of Fingolimod in Bulk Drug by Spectrophotometric Method as Per ICH Guidelines



Address:   Somsubhra Ghosh*, V. Laxmi Prasanna, B. Sowjanya, Dr. David Banji
Department of Pharmaceutical Analysis and Quality Assurance, Nalanda College of pharmacy, Cherlapally, Nalgonda, Andhra Pradesh -500081, India.
*Corresponding Author
DOI No:

ABSTRACT:
The present research work discusses the development of UV Spectrophotometric method for the determination of Fingolimod in bulk drug. The present method is simple, rapid, accurate, precise and economical. Absorption maxima of the drug was found to be 220 nm for Fingolimod in water solvent system. Water was used as solvent for this method. The method is applied to bulk drug form and best results are obtained for accuracy, precision and linearity over a range of 4-12µg/ml for Fingolimod. The percentage recovery was found to be 98.9% for Fingolimod. Results were analysed and validated for various parameters as per ICH guidelines.
KEYWORDS:
Fingolimod, UV, Validation.
Cite:
Somsubhra Ghosh, V. Laxmi Prasanna, B. Sowjanya, David Banji. Analytical Method Development and Validation of Fingolimod in Bulk Drug by Spectrophotometric Method as Per ICH Guidelines. Asian J. Research Chem 7(1): January 2014; Page 55-57.
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