Journal :   Asian Journal of Research in Chemistry

Volume No. :   7

Issue No. :  10

Year :  2014

Pages :   841-845

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Synthesis of Some Quinolino Substituted Benzimidazole Derivatives as Possible Antibacterial Agents



Address:   Sukhen Som*, Mohammed Saif ulla Khan, Mohamed Khaleel, Nirmal T. Havannavar
Department of Pharmaceutical Chemistry, M.M.U College of Pharmacy, K.K. Doddi, Ramanagara- 562159, Karnataka. India
*Corresponding Author
DOI No:

ABSTRACT:
The present study deals with the synthesis and evaluation of antibacterial activity of various quinolino substituted benzimidazole derivatives coupled with different amines. The derivatives were synthesized in moderate to good yields. The structural characterizations were performed based on their analytical data and IR, 1H NMR & Mass spectral studies. All the compounds were subjected for antibacterial screening, among them 4a and 4e showed good activity against the organisms used. The antibacterial activity studies suggested that these derivatives may be developed further to prove useful in future drug development.
KEYWORDS:
Quinoline, benzimidazole, quinolino benzimidazole.
Cite:
Sukhen Som, Mohammed Saif ulla Khan, Mohamed Khaleel, Nirmal T. Havannavar. Synthesis of Some Quinolino Substituted Benzimidazole Derivatives as Possible Antibacterial Agents. Asian J. Research Chem. 7(10): October- 2014; Page 841-845.
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