Journal :   Asian Journal of Research in Chemistry

Volume No. :   7

Issue No. :  11

Year :  2014

Pages :   950-953

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Synthesis and Antimicrobial Screening of Some 4-Substituted-3-Chloro-2-Oxo-Azetidine Derivatives



Address:   Rakesh Patel1* and Anil Bhandari2
1Charak Institute of Pharmacy, Mandleshwar (Khargone) M P
2Department of Pharmacy, Jodhpur National University, Jodhpur (Raj)
*Corresponding Author
DOI No:

ABSTRACT:
A new series of 2-oxo-azetidine derivatives of isoniazid have been synthesized and evaluated for their Anti-bacterial, Antifungal and Anti-tubercular activity. Synthesized compounds show significant activity against bacterial, fungal and mycobacterium strains. Their structures were established on the basis of elemental analysis, IR, 1H NMR and Mass Spectral data.
KEYWORDS:
INZ, Isoniazid, azetidine, antimycobacterial, TB.
Cite:
Rakesh Patel, Anil Bhandari. Synthesis and Antimicrobial Screening of Some 4-Substituted-3-Chloro-2-Oxo-Azetidine Derivatives. Asian J. Research Chem. 7(11): November, 2014; Page 950-953.
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