Journal :   Asian Journal of Research in Chemistry

Volume No. :   7

Issue No. :  11

Year :  2014

Pages :   905-908

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Synthesis and Antifungal Screening of Novel Pyrimidine-carbonitriles

Address:   Chetan M. Bhalgat*, B. Ramesh*
Department of Pharmaceutical Chemistry, Sri Adichunchanagiri College of Pharmacy, B.G.Nagara-571448, Nagamangala (Tq.), Mandya (Dist.), Karnataka, India.
*Corresponding Author

In the present study, a series of novel pyrimidines were synthesized. Structures of the synthesized compounds were established by IR, 1H NMR and mass spectral data. All the newly synthesized compounds were screened for their in vitro antifungal activities. Among the compounds tested, few were found to be most effective antifungal agents. The results revealed that the synthesized compounds may be potential lead for future drug discovery.
Pyrimidine; Synthesis; Spectral analysis; Antifungal activity.
Chetan M. Bhalgat, B. Ramesh. Synthesis and Antifungal Screening of Novel Pyrimidine-carbonitriles. Asian J. Research Chem. 7(11): November, 2014; Page 905-908.
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