Journal :   Asian Journal of Research in Chemistry

Volume No. :   7

Issue No. :  11

Year :  2014

Pages :   909-912

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Synthesis, Characterization and Antimicrobial Activity of Amino acids and Heterocyclic amines Coordinating Cu(II) Complexes



Address:   Md. Abul Bashar1, Shejuty aktar1, Md. Abdul Alim Al-Bari2, Md. Faruk Hossen1, M. Saidul Islam1 and Md. Kudrat-E-Zahan1*
1Inorganic Research Laboratory, Department of Chemistry, University of Rajshahi, Rajshahi-6205, Bangladesh.
2Pharmaceutical Microbiology Research Laboratory, Department of Pharmacy, University of Rajshahi, Rajshahi-6205, Bangladesh.
*Corresponding Author
DOI No:

ABSTRACT:
The mixed ligand complexes of Cu(II) with amino acids and heterocyclic amines have been synthesized and characterized on the basis of metal estimation, conductivity and magnetic measurements, infrared spectra and electronic spectra studies. The complexes were of [M(DA)2L2] or [M(DA)L2] where M = Cu(II) and DA= deprotonated amino acids as a primary ligand, such as glycine and cysteine; L= heterocyclic amines as a secondary ligand, such as quinoline, isoquinoline pyridine, 1,10-phenanthroline, 8-hydroxyquinoline, 2-picoline, 4-picoline. Antibacterial activity of the complexes has been examined against six (gram positive and gram negative) pathogenic bacteria by disc diffusion method and compared with that of standard antibiotic (Kanamycin). The complexes have been found to have moderate to strong antibacterial activity against the tested bacteria. All the compounds showed positive results that they are biologically active.
KEYWORDS:
Transition metal complex, spectra, Antimicrobial activity, Heterocyclic amines.
Cite:
Abul Bashar, Shejuty aktar, Abdul Alim Al-Bari, Faruk Hossen, Saidul Islam, Kudrat-E-Zahan. Synthesis, Characterization and Antimicrobial Activity of Amino acids and Heterocyclic amines Coordinating Cu(II) Complexes. Asian J. Research Chem. 7(11): November, 2014; Page 909-912.
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