Journal :   Asian Journal of Research in Chemistry

Volume No. :   7

Issue No. :  2

Year :  2014

Pages :   120-124

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Synthesis and characterization of 2-(2,4-dinitrophenylsulphanyl)-1H-benzimidazole derivatives



Address:   Mohan Rao Gangula and Vijaya Kumar Baru*
Medicinal Chemistry Laboratory, Research Center, C. K. M. Arts and Science College, Kakatiya University, Warangal-506 006, Andhra Pradesh, India.
*Corresponding Author
DOI No:

ABSTRACT:
In this article we focused on the synthesis and characterization of [2-(2,4-dinitrophenylsulfanyl)benzimidazol-1-yl]acetic acid(substituted-benzylidene)hydrazides (7a-g) and 5-[2-(2,4-dinitrophenylsulfanyl)benzimidazol-1-ylmethyl]-[1,3,4]-oxadiazole-2-thiol (8) derived from 2-{2-[(2,4-dinitrophenyl)sulphanyl]-1H-benzimidazol-1-yl}ethanohydrazide (6). Compound 6 was achieved from 1H-benzimidazole-2-yl-(2,4-dinitrophenyl)sulphide (4) with ethyl chloroacetate followed by treatment with hydrazine hydrate. The newly synthesized compounds were characterized by elemental analysis, IR, 1H NMR and Mass spectral data.
KEYWORDS:
1H-Benzimidazole-2-thiol; acetic acid ethyl ester; ethanohydrazide; oxadiazole-2-thiol.
Cite:
Mohan Rao Gangula, Vijaya Kumar Baru. Synthesis and characterization of 2-(2,4-dinitrophenylsulphanyl)-1H-benzimidazole derivatives. Asian J. Research Chem. 7(2): February 2014; Page 120-124.
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