Journal :   Asian Journal of Research in Chemistry

Volume No. :   7

Issue No. :  2

Year :  2014

Pages :   137-140

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Synthesis and anti-tubercular activity of some n-substituted and 2-substituted benzimidazole derivatives.



Address:   Pankaj S. Kore*, Sachin G. Lokpaure, Somkant V. Jawarkar, S K. Mohite, C S. Magdum
Department of Pharmaceutical chemistry. KES’s Rajarambapu College of Pharmacy, Kasegaon. Maharashtra (India)
*Corresponding Author
DOI No:

ABSTRACT:
The two series of N-substituted and 2-substituted benzimidazole derivatives, viz. 1-benzyl-2-substituted benzimidazole and 1-(p- chloro phenyl)-2-substituted benzimidazole have been synthesized and tested for their anti-tubercular activities. These compounds have been screened for their anticonvulsant activity, the compound 1A, 1G was found to possess significant anti tubercular activity as compared with Rifampicin.
KEYWORDS:
Benzimidazole derivatives anti-bacterial, anticonvulsant and anti-tubercular activities.
Cite:
Pankaj S. Kore, Sachin G. Lokpaure, Somkant V. Jawarkar, S K. Mohite, C S. Magdum. Synthesis and anti-tubercular activity of some n-substituted and 2-substituted benzimidazole derivatives. Asian J. Research Chem. 7(2): February 2014; Page 137-140.
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