Journal :   Asian Journal of Research in Chemistry

Volume No. :   7

Issue No. :  3

Year :  2014

Pages :   251-255

ISSN Print :  0974-4169

ISSN Online :  0974-4150


Registration

Allready Registrered
Click to Login

Synthesis and Identification (Oxazepine, Pyrazole, Isoxazole) compounds from 2-Aminobenzimidazole



Address:   Shaimaa Adnan1*, Kasim Hassan2, Hassan Thamer3
1College of Education, University of Al-Qadisiya Iraq
2College of Science, University of Babylon Iraq
3College of Education for Women, University of Kufa Iraq
*Corresponding Author
DOI No:

ABSTRACT:
This research involved heterocyclic compounds such as (oxazepine derivatives , pyrazol derivatives,isoxazole derivatives), were prepared by reaction 2-aminobenzaldehyde with salicylaldehyde to get azo compound (5-((1H-benzo [d] imidazol -2-yl)diazenyl)-2-hydroxybenzaldehyde) (1) ,which react (in acid medium ) with 4-Bromoaniline to get 4-((1H-benzo[d]imidazol-2-yl)diazenyl)-2-(((4-bromophenyl) imino)methyl)phenol (2) , and react with 4-aminobenzoicacid to get 1-(4-((5-((1H-benzo [d]imidazol-2-yl)diazenyl)-2-hydroxybenzylidene)amino)phenyl) ethanone (3) (both shiff base) . in other side ,(1) react ( in base medium ) with 4-Bromoacetophenon to get 3-(5-((1H-benzo[d]imidazol-2-yl)diazenyl)-2-hydroxyphenyl)-1-(4-bromophenyl)prop-2-en-1-one (4) ,and react with 4-hydroxyacetophenone to get 3-(5-((1H-benzo[d]imidazol-2-yl)diazenyl)-2-hydroxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one (5) (both chalcone derivatives). (2) and (3) react with phthalic anhydride and malic anhydride to get 3-(5-((1H-benzo[d]imidazol-2-yl)diazenyl)-2-hydroxyphenyl)-4-(4-bromophenyl)-3,4-dihydrobenzo [e] [1,3]oxazepine-1,5-dione (6), 3-(5-((1H-benzo[d]imidazol-2-yl)diazenyl)-2-hydroxyphenyl)-4-(4-acetylphenyl)-3,4-dihydrobenzo[e] [1,3]oxazepine-1,5-dione (7) , 2-(5 -((1H-benzo[d]imidazol-2-yl)diazenyl)-2-hydroxy phenyl) -3-(4-bromophenyl)-2,3-dihydro-1,3-oxazepine-4,7-dione (8) , 2-(5-((1H-benzo[d]imidazol-2-yl)diazenyl)-2-hydroxyphenyl)-3-(4-acetylphenyl)-2,3-dihydro-1,3-oxazepine-4,7-dione(9) .(oxazepine derivatives) (4) and (5) react with hydrazinhydrate to get 4-((1H-benzo[d]imidazol-2-yl)diazenyl)-2-(3-(4-bromophenyl)-4,5-dihydro-1H-pyrazol-5-yl)phenol (10) , 4-((1H-benzo[d]imidazol-2-yl)diazenyl)-2-(3-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-5-yl)phenol (11) , and react with phenylhydrazine to get 4-((1H-benzo[d]imidazol-2-yl)diazenyl)-2-(5-(4-bromophenyl)-1-phenyl-2,3-dihydro-1H-pyrazol-3-yl)phenol(12),4-((1H-benzo[d]imidazol-2-yl)diazenyl)-2-(5-(4-hydroxyphenyl)-1-phenyl-2,3-dihydro-1H-pyrazol-3-yl)phenol (13) (pyrazol derivatives).
KEYWORDS:
2-aminobenzoimidazole , pyrazol , isoxazole, chalcone, schiff base.
Cite:
Shaimaa Adnan, Kasim Hassan, Hassan Thamer. Synthesis and Identification (Oxazepine, Pyrazole, Isoxazole) compounds from 2-Aminobenzimidazole. Asian J. Research Chem. 7(3): March 2014; Page 251-255.
[View HTML]      [View PDF]



Visitor's No. :   126875