Journal :   Asian Journal of Research in Chemistry

Volume No. :   7

Issue No. :  6

Year :  2014

Pages :   580-585

ISSN Print :  0974-4169

ISSN Online :  0974-4150


Registration

Allready Registrered
Click to Login

Anti Diabetic and Anti Ulcer Activity of Ethanolic Flower Extract of Jasminum sambac in Rats



Address:   B. Rambabu1, K.S.K Rao Patnaik2
1Department of Pharmacology, Geethanjali College of Pharmacy, Cheryaal, Keesara, Ranga Reddy District, Andhra Pradesh, India- 501301
2Department of Technology, University College of Technology, Osmania University, Hyderabad, Andhra Pradesh, India- 501301
*Corresponding Author
DOI No:

ABSTRACT:
The present study was planned to evaluate the antidiabetic potential as well as antiulcer activity of flower extract of J. sambac. The diabetic activity was studied by oral glucose tolerance test, alloxan induced diabetes, streptozotocin induced diabetes models. The antiulcer activity was studied in rats in which gastric ulcers were induced by oral administration of ethanol or by pyloric ligation. Ranitidine, sucralfate, Glibenclamide were used as standards. The blood glucose levels of test extract treated animals were found to be significantly less in all the models compared to diabetic control. Similarly the ulcer index in the test extract treated animals was found to be significantly less in all the models compared to vehicle control animals. The anti-diabetic and antiulcer activities of J. sambac extract were however, less than that of standard. Our results suggest that J. sambac extract possesses significant antidiabetic property as well as antiulcer property.
KEYWORDS:
J. sambac, alloxan induced diabetes, streptozotocin induced diabetes models. Ranitidine, sucralfate, Glibenclamide.
Cite:
B. Rambabu, K.S.K Rao Patnaik. Anti Diabetic and Anti Ulcer Activity of Ethanolic Flower Extract of Jasminum sambac in Rats. Asian J. Research Chem. 7(6): June 2014; Page 580-585.
[View HTML]      [View PDF]



Visitor's No. :   126943