Journal :   Asian Journal of Research in Chemistry

Volume No. :   7

Issue No. :  7

Year :  2014

Pages :   649-652

ISSN Print :  0974-4169

ISSN Online :  0974-4150


Registration

Allready Registrered
Click to Login

Synthesis, Characterization and Antimicrobial Screening of Some Novel Chromonyl Chalcones



Address:   V.P. Sharma1 and Rakesh Kumar2*
1Department of Chemistry, Meerut College, Meerut (UP) India.
2Department of Chemistry, M.M.M. (P.G.) College, Bhatpar Rani, Deoria (UP) India, 274702.
*Corresponding Author
DOI No:

ABSTRACT:
Synthesis of some novel 6-acetyl-2-aryl/furyl chromones [4(a-b)] by Friedal-Craft’s acylation of 2-aryl/furyl chromones [3(a-b)] and 1-(2’-aryl/furyl chromon-6’-yl)-3-aryl or heteroarylprop-2-en-1-ones [5(a-f)] by Claisen-Schmidt condensation is being reported in this publication. The synthesized compounds have been characterized by elemental analysis, FT-IR and PMR spectral data. The synthesized compounds have been evaluated for their antibacterial and antifungal activities. Most of the compounds have been found moderately active when compared with the reference standard drugs.
KEYWORDS:
Chromones, Chalcones, Friedal-Craft’s acylation, Claisen-Schmidt condensation, antifungal and antibacterial activity.
Cite:
V.P. Sharma, Rakesh Kumar. Synthesis, Characterization and Antimicrobial Screening of Some Novel Chromonyl Chalcones. Asian J. Research Chem. 7(7): July 2014; Page 649-652.
[View HTML]      [View PDF]



Visitor's No. :   209492