Journal :   Asian Journal of Research in Chemistry

Volume No. :   7

Issue No. :  8

Year :  2014

Pages :   698-701

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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A Facile Synthesis of 2, 3-Dimethyl Benzocyclohepten-5-one

Address:   Prasad Gundepaka1,2,3, Srinivas Nerella4, Shravankumar Kankala4, Mukkanti Kagga2, Chandra Sekhar Vasam1*
1Department of Chemistry, Satavahana University, Karimnagar, India-505 001.
2Centre for Pharmaceutical Science, Institute of Science and Technology, JNTU, Hyderabad, India.
3Inogent Laboratories Private Limited,( A GVK BIO Company), Nacharam, Hyderabad, India
4Department of Chemistry, Kakatiya University, Warangal, India-506 009.
*Corresponding Author

The use of lithium chloride in boiling dimethylformamide has been shown to give high yields of 2,3-dimethyl benzocyclohepten-5-one from 2,3-dimethyl-6,6-dibromo-6,7,8,9-tetrahydrobenzocyclohepten-5-one . Similar elimination occurs from 2,3-dimethyl-6,9-dibromo-6,7,8,9-tetrahydrobenzo- cyclohepten-5-one to give 2,3-dimethyl benzocyclohepten-5-one.
Lithium chloride, dimethylformamide, NBS, cyclohepten-5-one.
Prasad Gundepaka, Srinivas Nerella, Shravankumar Kankala, Mukkanti Kagga, Chandra Sekhar Vasam. A Facile Synthesis of 2, 3-Dimethyl Benzocyclohepten-5-one. Asian J. Research Chem. 7(8): August 2014; Page 698-701.
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