Journal :   Asian Journal of Research in Chemistry

Volume No. :   7

Issue No. :  8

Year :  2014

Pages :   734-747

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Synthesis of Heterocyclic Compounds from Imine and Study of Chromatography Applications



Address:   Marwa T. Khattar1, Dr. Nagham M. Aljamali2*, Dr. Kasim K. Alasadi3
1M. Sc. Researcher, Chem. Dept., College of Education, Univ. of Kufa, Iraq.
2Assist. Prof., Chem. Dept., College of Education, Univ. of Kufa, Iraq.
3Assist. Prof., College of Science, Univ. of Kufa, Iraq
*Corresponding Author
DOI No:

ABSTRACT:
The aim of this work, synthesis of heterocycles included more than one hetero atom like (N, S, O) to produce various cycles [3-8] membered ring. This work involved five parts, included synthesis of compounds [1-20] first part includes synthesis of three compounds [1,11,17] through reaction between 4-alimethyl amino benzaldehyde with different primary aromatic amines to give (schiff bases ), second part involved synthesis of compounds [2, 1218, 20] from reaction between schiff bases with (maliec anhydride m, cystiene, 3,5dinitro salcylic acid , 0-thiol benzoic acid, alanine ) to give (oxazepine, imidazolidine, oxazine ) third part synthesis of diazepine compounds [3-5] from reaction between oxazepine with (hydro guandine, thiosimecarbazide, thiourea ) four part involved synthesis of compounds [6-10] from reaction between Diazepine with (di chloro methane, benzoic acid, oxalic acid, di chloro ethane ) to give (three, four, five) rings, five part involved of compounds [13-16] from reaction between five membered with (phthalic anhydride, malic anhydride, oxalic acid, dichloro ethane) to give (three, five, six, eight), six part include: study of chromatography. The structure of these compounds were characterized by (H.NMR, FI.IR, C.H.N) -techniques and their melting points, then study of chromatography behavior.
KEYWORDS:
Oxazepine, diazepine, maziridine, schiff base, melamine, four membered, eight membered.
Cite:
Marwa T. Khattar, Nagham M. Aljamali, Kasim K. Alasadi. Synthesis of Heterocyclic Compounds from Imine and Study of Chromatography Applications. Asian J. Research Chem. 7(8): August 2014; Page 734-747.
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