Journal :   Asian Journal of Research in Chemistry

Volume No. :   8

Issue No. :  5

Year :  2015

Pages :   299-306

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Synthesis and Screening of Mcrex-1

Address:   Nikhat F. 1*, Satyanarayana D.2, Shastry C.3, Thouheed A.3, Moid A.3
1Department of Pharmacy, AIKTC School of Pharmacy, New Panvel, Mumbai.
2Department of Pharmaceutical Chemistry, NGSMIPS, Deralakatte, Mangalore.
3Department of Pharmaceutical Chemistry, VIP Sciences, Rajahmundry, AP.
*Corresponding Author
DOI No: 10.5958/0974-4150.2015.00050.4

Methanol extract of dried leaves of Momordica charantia Linn (Cucurbitaceae), was investigated for anti-hyperglycemic activity in CTZ induced diabetics rat model, the results shows a significant reduction of blood glucose level to normal when compared with standard. The activity guided extract, subjected to isolation, which led to getting five bioactive constituents, among which one molecule selected for screening and synthesis.
Momordica charantia Linn, diabetics, anti-hyperglycemic,
Nikhat F. , Satyanarayana D., Shastry C., Thouheed A., Moid A.. Synthesis and Screening of Mcrex-1. Asian J. Research Chem 8(5): May 2015; Page 299-306.
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