Journal :   Asian Journal of Research in Chemistry

Volume No. :   8

Issue No. :  5

Year :  2015

Pages :   362-368

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Review article on 2, 5-Disubstituted-1, 3, 4-Thiadiazole Derivatives and its Pharmacological Activities



Address:   Preety Mishra, Arvind Kumar Singh*, Rohit Tripathi, Alok Giri
Kashi Institute of Pharmacy, MS-23 Varanasi-Allahabad Highway, Mirzamurad, Varanasi (UP)
*Corresponding Author
DOI No: 10.5958/0974-4150.2015.00060.7

ABSTRACT:
Heterocyclic compounds are the nucleus of the compound that provides life to the compound. It occupies the central position. In recent years it has been found that 1,3,4-thiadiazole and derivatives had gained many importance because of having extensive pharmacological activities, possibly due to the presence of toxophoric N2C2S moiety. It possess unique anti-inflammatory, analgesic, antimicrobial, anticonvulsant, antidiabetic, antitumor, antiviral activities. In the pursuit and design of new drugs, the development of hybrid molecules through the combination of different molecules in one frame may lead to compounds with interesting biological profiles. This review presents the recently synthesized 1,3,4-thiadiazole derivatives having important biological activities.
KEYWORDS:
1, 3, 4-thiadiazoles, Pharmacological activities.
Cite:
Preety Mishra, Arvind Kumar Singh, Rohit Tripathi, Alok Giri. Review article on 2, 5-Disubstituted-1, 3, 4-Thiadiazole Derivatives and its Pharmacological Activities. Asian J. Research Chem 8(5): May 2015; Page 362-368.
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