Journal :   Asian Journal of Research in Chemistry

Volume No. :   8

Issue No. :  7

Year :  2015

Pages :   441-444

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Comparative evaluation of marketed formulations of Metformin HCl. available in India



Address:   S. J. Daharwal1* , S Prakash Rao2, Vijay Kumar Singh2, Chandraprakash Dwivedi 2, Veena D. Singh1
1University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur-492010, Chhattisgarh, India.
2Columbia Institute of Pharmacy, Tekari, Near Vidhan sabha Raipur, C.G. 493111, India
*Corresponding Author
DOI No: 10.5958/0974-4150.2015.00070.X

ABSTRACT:
Metformin HCl is an oral Anti-diabetic drug belongs to the class of biguanide derivatives commonly used to treat type 2 diabetes mellitus. The study was conducted to assess the comparative in-vitro quality control parameters through the evaluation of mechanical strength, dissolution study in buffer solution, content and weight uniformity between the commercially available conventional and modified (sustained release) tablets of different brand of Metformin in India. It can be concluded that standard quality control parameters always should be maintained not only for Metformin but also for all kinds of medicine for getting better drug products.
KEYWORDS:
Metformin HCl, comparative, quality control parameters, evaluation.
Cite:
S. J. Daharwal, S Prakash Rao, Vijay Kumar Singh, Chandraprakash Dwivedi, Veena D. Singh. Comparative evaluation of marketed formulations of Metformin HCl. available in India. Asian J. Research Chem. 8(7): July- 2015; Page 441-444.
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