Journal :   Asian Journal of Research in Chemistry

Volume No. :   9

Issue No. :  12

Year :  2016

Pages :   674-678

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Zinc Sulfamate Catalysed Synthesis of Trisubstituted Imidazole

Address:   Jairaj K Dawle1*, Suryawanshi V B2, S R Mathapati3, A S Bondge4, K I Momin5
1Reserch Lab of Pure and Applied Chemistry, Maharashtra Mahavidhyalaya, Nilanga, Dist: Latur.
2Department of Chemistry, K M C College, Khopoli, Dist Raigad.
3Department of Chemistry, S. M. P. College, Murum, Omerga, Dist: Osmanabad.
4Department of Chemistry, Shivneri Mahavidhyalaya, Shirur Anantpal, Dist Latur.
5Department of Chemistry, Rajshri Shahu Mahavidhyalaya, Latur.
*Corresponding Author
DOI No: 10.5958/0974-4150.2016.00093.6

Numerous imidazole derivatives are reported as pharmacological agents like azomycin, clotrimazole, Miconazole, ergothionine, clonidine and moxonidine. One of the most important applications of imidazoles derivatives are treatment for denture and cancer therapy. Imidazoles are in general, well known to possess, anti-cancer activity. These compounds are 5 membered planar ring, soluble in water and other polar solvents. Radziszewski and Jaapproposed the first synthesis of the imidazole corein 1882, starting from 1,2-dicarbonyl compounds, aldehydes and ammonia to obtain 2,4,5-triphenylimidazole [1, 2].
Imidazole, Zinc Sulphate, trisubstitution etc.
Jairaj K Dawle, Suryawanshi V B, S R Mathapati, A S Bondge, K I Momin. Zinc Sulfamate Catalysed Synthesis of Trisubstituted Imidazole. Asian J. Research Chem. 2016; 9(12): 674-678.
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