Journal :   Asian Journal of Research in Chemistry

Volume No. :   9

Issue No. :  12

Year :  2016

Pages :   641-648

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Microwave Assisted Synthesis, Spectral Studies and Biological Evaluation of Some Benzimidazole Derivatives



Address:   Zeki A. Naser Al-Shamkhani
Dept. of Chemistry, College of Science, University of Basrah, Basrah-Iraq
*Corresponding Author
DOI No: 10.5958/0974-4150.2016.00088.2

ABSTRACT:
Benzimidazole (A) was synthesis by reaction of phenylenediamine with 4-p-amino benzaldehyde and then Schiff base synthesis by reaction amino benzimidazole with terphthaldehyde. Azetidinone (C) and Thaizolidinone (D) were also synthesized by reaction benzimidazole Schiff base with acetyl chloride and mercpto acetic acid respectively. These compounds have been synthesis by microwave irridation and characterized by M.P., TLC, CHN, UV, FT-IR, 1HNMR, and 13CNMR. The biological screening data of the synthesized compounds were also studied.
KEYWORDS:
Microwave, Benzimidazole, Schiff base, Azetidinone, Thaizolidinone, Anti-bacterial.
Cite:
Zeki A. Naser Al-Shamkhani. Microwave Assisted Synthesis, Spectral Studies and Biological Evaluation of Some Benzimidazole Derivatives. Asian J. Research Chem. 2016; 9(12): 641-648.
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