Journal :   Asian Journal of Research in Chemistry

Volume No. :   9

Issue No. :  3

Year :  2016

Pages :   107-112

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Synthesis and Biological Evaluation of Novel 1,3,4 -Thiadiazole Heterocyclic Derivatives as Novel Anti-Microbial Agents



Address:   Dr. P. Thriveni, M. Hari Krishna, K. Murali, T. Sekhar
Department of Chemistry, Vikrama Simhapuri University, Nellore-524003, A.P., India.
*Corresponding Author
DOI No: 10.5958/0974-4150.2016.00019.5

ABSTRACT:
Heterocyclic compounds are commonly used Scaffolds on which pharmacophores are arranged to provide potent and selective drugs. This is especially true for ?ve-membered ring heterocyclic compounds, which serve as the core components of many substances that possess a wide range of interesting biological activities. New series of 1,3,4- Thiadiazole derivatives were synthesized From Benzyl Isocynate and Acid hydrazide, by using P-TsCl in NMP, The Novel Derivatives have been screened for their antimicrobial activity.
KEYWORDS:
1,3,4- Thiadiazoles, Synthesis, Anti-bacterial activity and Anti- Fungal activity.
Cite:
P. Thriveni, M. Hari Krishna, K. Murali, T. Sekhar. Synthesis and Biological Evaluation of Novel 1,3,4 -Thiadiazole Heterocyclic Derivatives as Novel Anti-Microbial Agents. Asian J. Research Chem. 9(3): Mar., 2016; Page 107-112.
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