Journal :   Asian Journal of Research in Chemistry

Volume No. :   9

Issue No. :  7

Year :  2016

Pages :   293-295

ISSN Print :  0974-4169

ISSN Online :  0974-4150


Registration

Allready Registrered
Click to Login

Validated UV- Spectroscopic estimation of Simvastatin Concentration in Bulk and Dosage form



Address:   Pramod Nanasaheb Katkade1, Ravindranath Bhanudas Saudagar2
1Department of Pharmacy, Pacific University, Udaipur, Rajasthan- 313003
2Department of Quality Assurance Techniques, KCT’s R. G. Sapkal College of Pharmacy, Anjaneri, Nashik
*Corresponding Author
DOI No: 10.5958/0974-4150.2016.00047.X

ABSTRACT:
A simple, accurate, precise, and sensitive a highly selective ultra violet spectrophotometric method has been developed for the estimation of drug in bulk and dosage form. It shows maximum absorbance at 238nm. The Beer-Lambert’s law was obeyed in the concentration range of 5-35µg/ml. The linear regression analysis data for calibration plots showed good linear relationship and obtain correlation factor for Simvastatin. The percentage recovery was found to be within range. Thus method was successfully applied for routine analysis of Simvastatin in bulk drug and dosage form.
KEYWORDS:
Simvastatin, UV- method, Spectrometric method, Determination.
Cite:
Pramod Nanasaheb Katkade, Ravindranath Bhanudas Saudagar. Validated UV- Spectroscopic estimation of Simvastatin Concentration in Bulk and Dosage form. Asian J. Research Chem. 2016; 9(7): 293-295.
[View HTML]      [View PDF]



Visitor's No. :   204649