Journal :   Asian Journal of Research in Chemistry

Volume No. :   9

Issue No. :  9

Year :  2016

Pages :   413-418

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Strategic Application of Synthon Disconnection Approach in the Synthesis Planning of a Bioactive Natural Product ‘Withasomnine’



Address:   Chittaranjan Bhanja1*, Satyaban Jena2
1Department of Chemistry, Dinakrushna College, Jaleswar, Balasore-756084 Odisha India
2Department of Chemistry, Utkal University, Bhubaneswar-751004, Odisha India.
*Corresponding Author
DOI No: 10.5958/0974-4150.2016.00062.6

ABSTRACT:
Chemical synthesis of bioactive compounds from natural sources is a part and parcel of drug discovery and development process. Developing new synthetic strategies and methods towards such compounds is therefore an attractive option for obtaining larger quantities of the natural product without putting strain on the natural resources. Designing synthetic routes for convergent and viable synthesis from readily available materials is very fundamental to natural product synthesis. In this paper, we endeavor to profile some synthesis schemes for a natural pyrazole alkaloid ‘Withasomnine’ in a novel way basing on Synthon Disconnection Approach.
KEYWORDS:
Bioactive, natural product, synthesis, Synthon disconnection approach, withasomnine.
Cite:
Chittaranjan Bhanja, Satyaban Jena. Strategic Application of Synthon Disconnection Approach in the Synthesis Planning of a Bioactive Natural Product ‘Withasomnine’. Asian J. Research Chem. 2016; 9(9): 413-418.
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