Journal :   Asian Journal of Research in Chemistry

Volume No. :   10

Issue No. :  2

Year :  2017

Pages :   106-114

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Synthesis and Characterization of Schiff Base CoII, NiII and CuII Complexes derived from 2-Hydroxy-1-naphthaldehyde and Ethylenediamine



Address:   Kadhiravansivasamy, S. Sivajiganesan, T. Periyathambi, V. Nandhakumar, M. Pugazhenthi
Department of Chemistry A.V.V.M Sri Pushpam College Poondi, Thanjavur, Tamilnadu, India
*Corresponding Author
DOI No: 10.5958/0974-4150.2017.00016.5

ABSTRACT:
New CoII, NiII and CuII complex has been synthesized and characterized by elemental analysis, UV-Vis, FT-IR and thermal analysis Binding of this CoII, NiII and CuII complex with calf thymus DNA was investigated by UV-Visible absorption, fluorescence spectroscopy techniques. The intrinsic binding constants Kb of complex with CT-DNA obtained from UV-Vis absorption studies. Further, the in vitro cytotoxic effect of the complexes examined on cancerous cell line, such as human breast cancer cells (MCF-7).
KEYWORDS:
CoII, NiII and CuII complex, DNA interaction, Electrochemical studies and cytotoxicity activity.
Cite:
Kadhiravansivasamy, S. Sivajiganesan, T. Periyathambi, V. Nandhakumar, M. Pugazhenthi. Synthesis and Characterization of Schiff Base CoII, NiII and CuII Complexes derived from 2-Hydroxy-1-naphthaldehyde and Ethylenediamine. Asian J. Research Chem. 2017; 10(2):106-114.
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