Journal :   Asian Journal of Research in Chemistry

Volume No. :   10

Issue No. :  3

Year :  2017

Pages :   291-296

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Synthesis, Characterization, Equilibrium Studies and Antibacterial Studies of Co(II) complex with Schiff base Ligand derived from Pyridoxal and 2,4-Dichlorobenzohydrazide



Address:   Kavitha R.1, Ch. Venkata Ramana Reddy2*, B. Sireesha1
1 Department of Chemistry, Nizam College, OU, Basheerbagh, Hyderabad-500001, Telangana, India.
2Department of Chemistry, Jawaharlal Nehru Technological University Hyderabad, Kukatpally, Hyderabad-500085, Telangana, India.
*Corresponding Author
DOI No: 10.5958/0974-4150.2017.00047.5

ABSTRACT:
The Co(II) metal (M) complex of 2,4-dichloro-N-((3-hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene)benzohydrazide (L) was synthesized and characterized by elemental analysis, molar conductance, magnetic moment measurements, LC-MS, IR, TGA and UV spectral studies. Irving-Rossetti titration method was employed to determine the acid dissociation constant of ligand and the stability constant of Co(II) complex in 70% (v/v) DMF-water medium at 0.1 M KNO3 ionic strength and 303K temperature. The spectroanalytical data indicate the composition of the complexes to be 1:2 (ML2) with octahedral geometry. The ligand and the complex were screened for their antibacterial activity against Gram positive and Gram negative bacteria using agar well diffusion method.
KEYWORDS:
Pyridoxal, Schiff base, Complex, Stability constant, Antibacterial activity.
Cite:
Kavitha R., Ch. Venkata Ramana Reddy, B. Sireesha. Synthesis, Characterization, Equilibrium Studies and Antibacterial Studies of Co(II) complex with Schiff base Ligand derived from Pyridoxal and 2,4-Dichlorobenzohydrazide. Asian J. Research Chem. 2017; 10(3):291-296.
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