Journal :   Asian Journal of Research in Chemistry

Volume No. :   10

Issue No. :  4

Year :  2017

Pages :   497-503

ISSN Print :  0974-4169

ISSN Online :  0974-4150


Registration

Allready Registrered
Click to Login

Microwave assisted synthesis of chitosan epoxy asparagine hydroxamate (CE-AH) Characterization and Study of its antimicrobial activity



Address:   Monika Singh*, Sangeeta Loonker
Department of Chemistry, Jai Narain Vyas University, Jodhpur (Rajasthan),-342001, India
*Corresponding Author
DOI No: 10.5958/0974-4150.2017.00081.5

ABSTRACT:
Green synthetic approaches are emerged as a remarkable technology for the production of biopolymer based novel derivatives. Microwave assisted synthesis method is considered as safe alternative to conventional physiochemical methods due to its environmental friendly nature. Chitosan was derivatized with epichlorohydrin, asparagine using microwave. After this the product was regenerated from the mixture of water and methanol (1:1)then washed with ethanol, methanol. Solvents like DMSO, DMF are used while synthesis. The characteristics of newly formed derivative was studied by Fourier transform Infrared spectrum(FT-IR), Thermogravimetric analysis(TGA), Nuclear Magnetic Resonance(NMR), Mass spectra, Scanning Electron Microscopy(SEM), elemental analysis etc. Antimicrobial activity was studied on different bacteria and fungi by well diffusion method.
KEYWORDS:
Microwave assisted synthesis, chitosan, asparagine, SEM, NMR, TGA antimicrobial activity.
Cite:
Monika Singh, Sangeeta Loonker. Microwave assisted synthesis of chitosan epoxy asparagine hydroxamate (CE-AH) Characterization and Study of its antimicrobial activity. Asian J. Research Chem. 2017; 10(4):497-503.
[View HTML]      [View PDF]



Visitor's No. :   204967