Journal :   Asian Journal of Research in Chemistry

Volume No. :   10

Issue No. :  6

Year :  2017

Pages :   719-724

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Catalyst Free Synthesis of Imines and their Biological Evaluation

Address:   Kalimoddin I. Momin1, Abhay S. Bondge2, Vikas B. Surawanshi3, Jairaj K. Dawale4*
1Rajarshi ShahuMahavidhyalaya, Latur, Maharashtra-413512, India.
2Shivneri College, ShirurAnantpal, Dist. Latur, Maharashtra- -413544, India.
3Department of Chemistry, KMC College, Khopoli, Maharashtra- -410203 India.
4Research Laboratory for Pure and Applied Chemistry, M. M. College, Nilanga, Dist. Latur, MH413521, India.
DOI No: 10.5958/0974-4150.2017.00122.5

An efficient route for the synthesis of aromatic imines has been developed using simple protocol at room temperature. The synthesis was completed by using commercially available starting material. Here we synthesized fourteen imines derivatives with excellent yield. Synthesized intermediates showed potent inhibition of Mycobacterium tuberculosis. The Schiff’s bases shown drug like properties and is a good starting point for further exploration in antituberculosis drug discovery.
Schiff’s bases, imines, biological activity, aldehydes, DMF.
Kalimoddin I. Momin, Abhay S. Bondge, Vikas B. Surawanshi, Jairaj K. Dawale. Catalyst Free Synthesis of Imines and their Biological Evaluation. Asian J. Research Chem. 2017; 10(6):719-724.
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