Journal :   Asian Journal of Research in Chemistry

Volume No. :   10

Issue No. :  6

Year :  2017

Pages :   845-851

ISSN Print :  0974-4169

ISSN Online :  0974-4150


Registration

Allready Registrered
Click to Login

Synthesisand Characterizationofvital6–arylPurinesandtheirBiologicalEvaluation



Address:   Kalimoddin I. Momin1, Abhay S. Bondge2, Vikas B. Surawanshi3,Jairaj K. Dawale4*
1Rajarshi ShahuMahavidhyalaya, Latur, Maharashtra-413512, India.
2Shivneri College, ShirurAnantpal, Dist. Latur, Maharashtra- -413544, India.
3Department of Chemistry, KMC College, Khopoli, Maharashtra- -410203 India.
4Research Laboratory for Pure and Applied Chemistry, M. M. College, Nilanga, Dist. Latur, MH413521, India.
*Corresponding Author
DOI No: 10.5958/0974-4150.2017.00141.9

ABSTRACT:
An efficient route has been developed for the synthesis of 6-aryl purines in water, the ecofriendly protocol allows the reaction smooth. The diverse scope of different boronic acids has shown and synthesized intermediates showed potent inhibition of Mycobacterium Tuberculosis. The synthesized derivatives characterized well by using spectroscopic techniques NMR, mass and IR analysis. This protocol allows diverse modification as well as synthesis of 6- aryl purine derivatives.
KEYWORDS:
Purine, drug, chloropurine, boronic acids, biological activity, TB.
Cite:
Kalimoddin I. Momin, Abhay S. Bondge, Vikas B. Surawanshi, Jairaj K. Dawale. Synthesisand Characterizationofvital6–arylPurinesandtheirBiologicalEvaluation. Asian J. Research Chem. 2017; 10(6):845-851.
[View HTML]      [View PDF]



Visitor's No. :   202701