Journal :   Asian Journal of Research in Chemistry

Volume No. :   11

Issue No. :  1

Year :  2018

Pages :   109-110

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Microwave assisted synthesis of 1,3,5-triazine containing [1,8]naphthyridine derivatives

Address:   Gandra Sandhya*, Garepalli Ganga Sravanthi
Nicholas fine Chemicals, Balanagar Hyderabad-500018 Telangana
*Corresponding Author
DOI No: 10.5958/0974-4150.2018.00022.6

2-Cyclopropyl-[1,8]naphthyridine-3-carboxylic acid ethyl ester (1) reacts with different aromatic aldehydes yields N-(2-Cyclopropyl-[1,8]naphthyridine-3-carbonyl)-guanidine (2). which on further treatment with aromatic nitriles to yield 4-(2-Cyclopropyl-[1,8]naphthyridin-3-yl)-6-phenyl-[1,3,5]triazin-2-ylamine (3a-e).
1,8-naphthyridine, nitriles, triazine, antibacterial activity.
Gandra Sandhya, Garepalli Ganga Sravanthi. Microwave assisted synthesis of 1,3,5-triazine containing [1,8]naphthyridine derivatives. Asian J. Research Chem. 2018; 11(1):109-110.
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