Journal :   Asian Journal of Research in Chemistry

Volume No. :   11

Issue No. :  2

Year :  2018

Pages :   217-220

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Synthesis, Characterization and AntimicrobialActivity of Some new 1,4 Diaryl-3-Methyl-6-Imino-4,7-Dihydro-1,3-Thiazino (5,4-d) Pyrazoles



Address:   A.K. Yadav*1, Mazhar Mehdi2*, Tasneem Fatima3
1Prasad Inst. of Technology, Jaunpur (U.P.)
2Asst. Prof.,Chemistry Dept. , Shia P G College, Lucknow (U.P.)
3Asst. Prof.,Chemistry Dept. , Dr. A.H.R. Shia Degree College Jaunpur (U.P.)
*CorrespondingAuthor
DOI No: 10.5958/0974-4150.2018.00041.X

ABSTRACT:
Pyrazolones (1) react with aromatic aldehydes to give 1-aryl-3 methyl-4-arylidene pyrazol-5-ones(2).. The condensation of 4-arylidene-pyrazol-5-ones (2) with thiourea/N-phenyl thiourea in alcoholic KOH led to formation of the title compounds 1,4-diaryl-3-methyl-6-imino-4,7-dihydro-1,3-thiazine (5,4-d) pyrazoles (3). The title compounds have been screened for their antibacterial activity against S. aureus andE.coli.
KEYWORDS:
Synthesis, Characterization, Antimicrobial Activity , new Pyrazoles
Cite:
A.K. Yadav, Mazhar Mehdi, Tasneem Fatima. Synthesis, Characterization and AntimicrobialActivity of Some new 1,4 Diaryl-3-Methyl-6-Imino-4,7-Dihydro-1,3-Thiazino (5,4-d) Pyrazoles. Asian J. Research Chem. 2018; 11(2):217-220.
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