Journal :   Asian Journal of Research in Chemistry

Volume No. :   11

Issue No. :  2

Year :  2018

Pages :   269-274

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Catalyst free Synthesis of Phenyl Hydrazones and their Biological Evaluation

Address:   Vikas B. Suryawanshi1, Kalimoddin I. Momin2 , Abhay S. Bondge3, Jairaj K. Dawale4*
1Department of Chemistry, KMC College, Khopoli, Maharashtra- -410203 India.
2Rajarshi Shahu College, Latur, Maharashtra-413512, India. 3Shivneri College, Shirur Anantpal, Dist. Latur, Maharashtra- -413544, India.
4Research Laboratory for Pure and Applied Chemistry, M. M. College, Nilanga, Dist. Latur, MH- 413521, India.
*Corresponding Author
DOI No: 10.5958/0974-4150.2018.00050.0

An efficient route for the synthesis of aromatic hydrazones has been developed using simple protocol in water. The synthesis was completed by using commercially available starting material. Synthesized intermediates showed potent inhibition of Mycobacterium tuberculosis. The protocol shows broad substrate scope. The phenyl hydrazine shown drug like properties and is a good starting point for further exploration in antituberculosis drug discovery.
Benzophenone, hydrazine hydrate, green, drug, ethanol.
Vikas B. Suryawanshi, Kalimoddin I. Momin , Abhay S. Bondge, Jairaj K. Dawale. Catalyst free Synthesis of Phenyl Hydrazones and their Biological Evaluation. Asian J. Research Chem. 2018; 11(2):269-274.
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