Journal :   Asian Journal of Research in Chemistry

Volume No. :   11

Issue No. :  2

Year :  2018

Pages :   279-281

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Eco friendly synthesis of N'-Arylidene-2-((7-bromo-2-methylpyrido[2,3-B]pyrazin-3-yl)oxy)acetohydrazides



Address:   Rajeshwari M
Telangana University Dichpally, Nizamabad, Telangana 503322
*Corresponding Author
DOI No: 10.5958/0974-4150.2018.00052.4

ABSTRACT:
5-bromo 2,3-diamino pyridine and ethylpyruvate react each other to form 7-bromo-2-methylpyrido[2,3-b]pyrazin-3-ol (1) which further reacts with ethylchloroacetate and formethyl 2-((7-bromo-2-methylpyrido[2,3-b]pyrazin-3-yl)oxy)acetate (2). Compound 2 on reaction with hydrazinehydrate gives 2-((7-bromo-2-methylpyrido[2,3-b]pyrazin-3-yl)oxy)acetohydrazide (3), which on condensation with different aldehydes produce N'-Arylidene-2-((7-bromo-2-methylpyrido[2,3-b]pyrazin-3-yl)oxy)acetohydrazides (4a-e).
KEYWORDS:
Heterocycles, Aldehydes, Antitumor Agents, Hydrogen Bond, Corrosion, Hormones.
Cite:
Rajeshwari M. Eco friendly synthesis of N'-Arylidene-2-((7-bromo-2-methylpyrido[2,3-B]pyrazin-3-yl)oxy)acetohydrazides. Asian J. Research Chem. 2018; 11(2):279-281.
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