Journal :   Asian Journal of Research in Chemistry

Volume No. :   11

Issue No. :  2

Year :  2018

Pages :   319-328

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Synthesis and Antibacterial Studies of 2-Pyrazoline based Bis Heterocycles



Address:   K. Babu
PG and Research Department of Chemistry, Rajah Serfoji Government College (Auto), Thanjavur, Tamil Nadu, India.
*Corresponding Author
DOI No: 10.5958/0974-4150.2018.00059.7

ABSTRACT:
Here in, I have described synthesis, spectral characterization and antibacterial activities of some novel five membered bis-heterocyclic compounds comprising both 2-pyrazoline and pyrazole related moiety. The target products were obtained by applying well known reactions such as, aldol condensation, diazotization, diazocoupling and cyclisation reactions. The structures of synthesized compounds were confirmed by the help of Melting point, TLC, FT-IR, 1H-NMR and 13C-NMR spectra. The invitro antibacterial activities were examined and most of the compounds showed very good inhibition zone against selective bacteria.
KEYWORDS:
Diazotization, Active methelene compounds, Aldol condensation, coupling reaction, Pyrazoline.
Cite:
K. Babu. Synthesis and Antibacterial Studies of 2-Pyrazoline based Bis Heterocycles. Asian J. Research Chem. 2018; 11(2):319-328.
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