Journal :   Asian Journal of Research in Chemistry

Volume No. :   11

Issue No. :  2

Year :  2018

Pages :   409-412

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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A Comparative study of Vilsmeier-Haack Formylation Reactions With Phenols Under Solvent Less And Solvent Conditions



Address:   Roopa Redamala1,2*, Ramchander Merugu2, K.C. Rajanna1
1Department of Chemistry, Osmania University Hyderabad, (A.P) - 500 007 India
2Department of Chemistry and Biochemistry, Mahatma Gandhi University, Nalgonda-508254 India
*Corresponding Author
DOI No: 10.5958/0974-4150.2018.00074.3

ABSTRACT:
The Vilsmeier-Haack reaction with phenols has been carried out under solvent free conditions and as well as solvent conditions. The reactants are taken in a mortar and grounded with a pestle for about 20 to 30 min at room temperature. The reactants are taken in a beaker and placed in microwave for about 30 secs to 1 min. The reactions afforded formyl derivatives in fairly good yields when a mixture of dimethyl formamide (DMF) and SOCl2 is used as VH reagent. Results of solvent free reactions are more superior over solution phase reactions with very good yields and far lesser reaction times.
KEYWORDS:
Formylation, V-H reaction, Phenols, solvent less, solvent free.
Cite:
Roopa Redamala, Ramchander Merugu, K.C. Rajanna. A Comparative study of Vilsmeier-Haack Formylation Reactions With Phenols Under Solvent Less And Solvent Conditions. Asian J. Research Chem. 2018; 11(2):409-412.
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