Journal :   Asian Journal of Research in Chemistry

Volume No. :   11

Issue No. :  2

Year :  2018

Pages :   477-484

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Synthesis of Pyranopyrazoles by using Chitosan Hydrogel as a green and recyclable catalyst



Address:   Kiran Patil1, 2*, Vasant Helavi2
1Department of Chemistry, Dr. Ghali College, Gadhinglaj, Maharashtra 416502, India
2Department of Chemistry, Rajaram College, Kolhapur, Maharashtra 416004, India
*Corresponding Author
DOI No: 10.5958/0974-4150.2018.00087.1

ABSTRACT:
Chitosan Hydrogel was used for a highly efficient one-pot, four component synthesis of 6-amino-3-methyl-5-cyano-4-aryl-1, 4-dihydropyrano [2, 3-c] pyrazoles from aromatic aldehydes, malononitrile, ethyl acetoacetate and hydrazine hydrate in water as solvent under classical heating. Using microwave heating, reaction times were shortened from 1hr to 2 min. The advantages of this method includes the use of water as a green solvent ,use of recyclable chitosan hydrogel as a green catalyst, short reaction time, easy work up, and excellent yields.
KEYWORDS:
4-component reaction, One-pot synthesis, Chitosan hydrogel, Water, Microwave Irradiation.
Cite:
Kiran Patil, Vasant Helavi. Synthesis of Pyranopyrazoles by using Chitosan Hydrogel as a green and recyclable catalyst. Asian J. Research Chem. 2018; 11(2):477-484.
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