Journal :   Asian Journal of Research in Chemistry

Volume No. :   11

Issue No. :  3

Year :  2018

Pages :   603-606

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Synthesis and Antibacterial Activity of Pyrazolo[5,1-c]Thieno[3,4-e][1,2,4] Triazin-6-Amide Derivatives



Address:   Balaraju V1,2, Yadaiah S1, Ramchander Merugu1, M. Jyothi1 , Laxminarayana Eppakayala2*
1Mahatma Gandhi University, Anneparthy, Nalgonda- 508 254 (Telangana) India
2Sreenidhi Institute of Science and Technology (Autonomous), Ghatkesar, Hyderabad-501 301 (Telangana) India.
*CorrespondingAuthor
DOI No: 10.5958/0974-4150.2018.00108.6

ABSTRACT:
A series of Pyrazolo[5,1-c]thieno[3,4-e] [1,2,4]triazin-6-amide derivatives were synthesized from 5-amino pyrazole and characterized by spectral analyses and their antibacterial activity was evaluated. Compound 5a was the most active among all the compounds synthesized compared to other compounds.
KEYWORDS:
5-amino pyrazole, 3-aminocrotononitrile, sulfur, 3-Bromopropionyl chloride, pyrazolothienotrizin.
Cite:
Balaraju V,, Yadaiah S, Ramchander Merugu, M. Jyothi , Laxminarayana Eppakayala. Synthesis and Antibacterial Activity of Pyrazolo[5,1-c]Thieno[3,4-e][1,2,4] Triazin-6-Amide Derivatives. Asian J. Research Chem. 2018; 11(3):603-606.
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