Journal :   Asian Journal of Research in Chemistry

Volume No. :   11

Issue No. :  4

Year :  2018

Pages :   710-712

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Novel Synthesis of Norepinephrine Thiocarbamides



Address:   D. T. Tayade1, A.A. Dhande2*
1Department of Chemistry, Government Vidarbha Institute of Science and Humanities, Amravati- 444604, Maharashtra State, India.
2Department of Chemistry, Government Vidarbha Institute of Science and Humanities, Amravati-444604, Maharashtra State, India.
*Corresponding Author E-mail:
DOI No: 10.5958/0974-4150.2018.00125.6

ABSTRACT:
A new series of norepinephrine thiocarbamides was synthesized by the interactions of norepinephrine with ethyl and phenyl isothiocyanates in acetone medium, to isolate 1,1-(1R)(3,4-Dihydroxyphenyl)-2-ethylthiocarbamidoethanol [DHPETC] and 1,1-(1R)(3,4-Dihydroxyphenyl)-2-phenylthiocarbamidoethanol [DHPPTC] respectively. The products thus synthesized in these reactions were characterized on the basis of conventional elemental analysis, chemical characteristics and through IR, PMR, CMR and Mass spectral analysis.
KEYWORDS:
Norepinephrine, isothiocyanates, norepinephrine thiocarbamides.
Cite:
D. T. Tayade, A.A. Dhande. Novel Synthesis of Norepinephrine Thiocarbamides. Asian J. Research Chem. 2018; 11(4):710-712.
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