Journal :   Asian Journal of Research in Chemistry

Volume No. :   11

Issue No. :  4

Year :  2018

Pages :   746-750

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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Study on the Synthesis, Structure and Antimicrobial activity of the new Mannich base and its Transition Metal Complexes Derived from Phthalimide



Address:   A. Balakrishnan1, Dr. A. Sankar2*
1Assistant Professor, PG and Research Department of Chemistry, Govt Arts College, Dharmapuri, Tamilnadu, India
2Assistant Professor, PG and Research Department of Chemistry, Kandaswami Kandars College, P. Velur, Tamilnadu, India
*Corresponding Author
DOI No: 10.5958/0974-4150.2018.00131.1

ABSTRACT:
Cyclic aromatic secondary amines, like phthalimides, and related compounds possess structural features, which makes them to exert potential biological activities and pharmaceutical applications. A new Mannich base has been synthesized from phthalimide and its transition metal complexes also were prepared. The Mannich base ligand was synthesized by using phthalimide, formaldehyde and piperidine. The ligand as well as the metal complexes were characterized by various physical methods. The structure of the synthesized compounds are confirmed by UV, IR, and 1H NMR spectroscopic techniques. The antimicrobial activity of the ligand and the complexes were examined using different bacteria by disc diffusion technique.
KEYWORDS:
Mannich base, Phthalimide, transition metal complex, and antimicrobial study.
Cite:
A. Balakrishnan, A. Sankar. Study on the Synthesis, Structure and Antimicrobial activity of the new Mannich base and its Transition Metal Complexes Derived from Phthalimide. Asian J. Research Chem. 2018; 11(4):746-750.
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