Journal :   Asian Journal of Research in Chemistry

Volume No. :   12

Issue No. :  4

Year :  2019

Pages :   225-230

ISSN Print :  0974-4169

ISSN Online :  0974-4150


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High Performance Liquid Chromatography-Inductively coupled plasma Mass Spectrometry

Address:   Dr. Bhavya Sri*, Amina Fatima, R. Swethasri, Dr. M Sumakanth
Department of Pharmaceutical Analysis, RBVRR Womenʼs College of Pharmacy, Barkatpura, Hyderabad, India
*Corresponding Author
DOI No: 10.5958/0974-4150.2019.00043.9

Speciation analysis has evolved into an valuable tool in human health risk evaluation, environmental survey and food quality control. The eventual impact of an element will be dictated by particular species of forms of the element, rather than its total concentration. Separation and detection of species of several elements in single analytical run can be accomplished by high performance liquid chromatography hyphenated to inductively coupled plasma mass spectrometry (HPLC/ICP-MS). Although various methods are available for speciation analysis. Yet, because of several advantages like versatility, robustness, sensitivity, and multielement capabilities HPLC-ICP-MS has become the most popular technique for element specific speciation studies. This review will focus on fundamentals of HPLC/ICP-MS, recent advancements and its recent applications in various fields.
speciation, robustness, sensitivity, advancements, applications.
Bhavya Sri, Amina Fatima, R. Swethasri, M Sumakanth. High Performance Liquid Chromatography-Inductively coupled plasma Mass Spectrometry. Asian J. Research Chem. 2019; 12(4):225-230.
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