Asian Journal of Research in Chemistry

ISSN

0974-4150 (Online)
0974-4169 (Print)


Submit Article

Modulation of Clonazepam Solubility using Solid Dispersion Technique Improves its Solubility and Bioavailability

Author(s): Hanaa A. Fattah, Hammad M. A., Nagia El-Megrab, Waleed Barakat, Ahmed Samir

Email(s): dr_scheva99@yahoo.com

DOI: Not Available

Address: Hanaa A. Fattah1, Hammad M. A.1, Nagia El-Megrab1, Waleed Barakat2 , Ahmed Samir1
1Department of Pharmaceutics, Faculty of Pharmacy, Zagazig University, Egypt.
2Department of Pharmacology, Faculty of Pharmacy, Zagazig University, Egypt.
*Corresponding Author

Published In:   Volume - 5,      Issue - 4,     Year - 2012


Keywords:

Cite this article:
Hanaa A. Fattah, Hammad M. A., Nagia El-Megrab, Waleed Barakat , Ahmed Samir. Modulation of Clonazepam Solubility using Solid Dispersion Technique Improves its Solubility and Bioavailability. Asian J. Research Chem. 5(4): April 2012; Page 446-455.

  View PDF



Recomonded Articles:

Pyridine and Its Biological Activity: A Review

Author(s): Prathima Patil, S.P. Sethy, T. Sameena, K. Shailaja

DOI:         Access: Open Access Read More

Synthesis and Biological Screening of Novel Aminoalkyl Substituted Azaphenothiazine

Author(s): P. Valentina, K. Ilango, Deepak Jain, Prerna Shukla

DOI:         Access: Open Access Read More

An Overview of Imidazole, Derivatives Ofimidazole and its Pharmacological Applications

Author(s): Rahul Godge, Amol Dighe, Piyusha Kolhe

DOI: 10.52711/0974-4150.2023.00012         Access: Open Access Read More

Review on Analgesic activity using Tail Immersion Method

Author(s): Snehal A. Rokade, Rupali. V. Jadhav

DOI: 10.52711/0974-4150.2022.00075         Access: Open Access Read More

Imidazole and its Biological Activities: A Review

Author(s): U. Sahoo, S. Biswal, S. Sethy, H.K.S. Kumar, M. Banerjee

DOI:         Access: Open Access Read More

Application of Chalcones in Synthesis of Novel 1, 5-Benzodiazepine Derivatives Containing Thieno [2, 3-d] Pyrimidine Core Unit and its Biological Activity Screening

Author(s): Virupakshi Prabhakar, Kondra Sudhakar Babu, L.K. Ravindranath, M. Sahanoor Basha, J. Latha

DOI: 10.5958/0974-4150.2017.00012.8         Access: Open Access Read More

Prodrug as a chemical delivery system: A Review

Author(s): Alka Verma, Bhupesh Verma, Sunil Kumar Prajapati, Kishu Tripathi

DOI:         Access: Open Access Read More

The Role and Significance of Rasa-Aushadhis in Ayurvedic Pharmacology: A Comprehensive Overview

Author(s): Shivani Koul, Shyama, Reetesh Ramnani, Anupam Srivastava

DOI: 10.52711/0974-4150.2025.00040         Access: Open Access Read More

Gastro Retentive Drug Delivery System: A Review

Author(s): Shahnawaz Ahmad, Vipul Singh, Dr. Sanjay Kumar Kushwaha

DOI: 10.52711/0974-4150.2023.00075         Access: Open Access Read More

Exploring Binding Affinities and Interactions of Benzimidazole Derivatives via AutoDock Molecular Docking Studies

Author(s): Rajat Sharma, Shilpa, Sanjiv Duggal

DOI: 10.52711/0974-4150.2025.00020         Access: Open Access Read More

Abbreviated New Drug Application Process: A Gift for The Industry and The Patients

Author(s): Hindustan Abdul Ahad, Haranath Chinthaginjala, Gangireddy Jayasimha Reddy, Pasupuleti Dheeraj Krishna, Syed Rahamathulla, Jyothi Vinay Krishna

DOI: 10.52711/0974-4150.2021.00056         Access: Open Access Read More

Biochemical evaluation of antidiabetic activity of Piper betel leaves extract in alloxan-induced diabetic rats

Author(s): K. Radhika, B. Kumaravel, V. Thamizhiniyan, S. Subramanian

DOI:         Access: Open Access Read More

In Silico Drug-Likeness, ADMET, Toxicity Profiling of Clinically Relevant Antidiabetic agents

Author(s): Ashwini Mandawade, Pruthvirajsing Pardeshi, Sukhsagar Khairnar, Ganesh Sonawane, Sunil Mahajan

DOI: 10.52711/0974-4150.2025.00036         Access: Open Access Read More

Aminothiophene and Schiff base derivative-synthesis, Density Functional theory, ADME study and it’s characterization

Author(s): Adinath R. Bhandwalakr, Rahul S. Bhondwe

DOI: 10.52711/0974-4150.2024.00053         Access: Open Access Read More

Bioaccumulation of trace elements in Cyprinus Carpio’s organs collected from Hammam Boughrara dam

Author(s): Zaineb Derrag, Nacéra Dali Youcef, Souheyla Boudjema

DOI: 10.5958/0974-4150.2021.00010.9         Access: Open Access Read More

A Comprehensive report on Solid Dispersions by Factorial Design

Author(s): Hindustan Abdul Ahad, Haranath Chinthaginjala, Syed Rahamtulla, Barji Prasanna Pallavi, Chakali Shashanka, Jangam Prathyusha

DOI: 10.52711/0974-4150.2021.00051         Access: Open Access Read More

Anti Obesity activity of Rhynchosia beddomei by using Progesteron induced Obesity in Mice, and Mono Sodium Glutamate Induced Obesity in rats.

Author(s): Habeeba Sultana, Tahseen Sameena, Hafsa Siddiqua, Kouser Unnisa

DOI: 10.5958/0974-4150.2017.00045.1         Access: Open Access Read More

Analysis of Midazolam in Small Volumes of Plasma Using High Performance Liquid Chromatography and UV-Detection Method: Pharmacokinetics of Midazolam in Rats

Author(s): Swapnil J. Dengle, Shriram M. Pathak, Chandra Mohan, Arumugam Karthik, Prashant Musmade, Krishnamurthy Bhat, Nayanabhirama Udupa

DOI:         Access: Open Access Read More

Anti Diabetic and Anti Ulcer Activity of Ethanolic Flower Extract of Jasminum sambac in Rats

Author(s): B. Rambabu, K.S.K Rao Patnaik

DOI:         Access: Open Access Read More

Adsorption and Partition Studies of Fluconzole

Author(s): Ashok A. Hajare, Mahesh N. Mali, Sushil Sarvagod, Sachin Kurane, Shweta Patwardhan, Arun S. Dange

DOI:         Access: Open Access Read More

Asian Journal of Research in Chemistry (AJRC) is an international, peer-reviewed journal devoted to pure and applied chemistry..... Read more >>>

RNI: Not Available                     
DOI: 10.5958/0974-4150 

Quick Links

Latest Issues

Popular Articles


Recent Articles



Development of rapid, simple and novel method for the validation of Abaloparatide and Teriparatide in Combined Dosage Form By RP-HPLC Method
Development and Evaluation of Efinaconazole Containing Potential Permeation enhancer for an enhanced Transungual Drug Delivery
Least Squares Modeling of Surface Tension of Alkanes
Physicochemical and Antimicrobial activity of Medicinal plant – Piper longum
A Perturbation Theory approach to Equation of State and Excess energy of Size-Asymmetric Square-Well Fluid Mixtures
Beyond the Bench: Statistical Software as the Engine for Pharmaceutical Development and Regulatory Success
Circular Economy, March of Mankind and the Vast vision for the Future
Determination of Clopidogrel Bisulphate from Pharmaceutical Dosage Form by Extractive Ion Pair Complex Colorimetric Method
Studies on the Formation of Metal Sulphate: 2-Furoic Acid Complexes (Metal: Mg, Mn, Fe, Ni, Cu, Zn, Cd)
Principle to Practice: Evaluating Analytical Methods in AGREE Prep with Green Analytical Chemistry
A Novel Tetradentate Thiazole-Based Schiff Base Ligand and its Binuclear Co(II), Ni(II), Cu(II) and Zn(II) Complexes: Synthesis, Spectral, Structural and Electrochemical Investigation
Synthesis, Characterization and Biological Studies of Schiff Bases of 2,6 diamino 4-hydroxy pyrimidine with P- Methoxysalicylaldehyde and Some Transition Metal Complexes
Comparative Estimation and Validation of Danicopan in Tablet Dosage Form and in Bulk Drug by Spectrophotometric Method
Phenolic compounds of Senna alata extracts and their Inhibitory activity of α-Glucosidase
Simple Extractive Spectrophotometric Method for Determination of Imatinib Mesylate by Reactive Dyes from Pharmaceutical Dosage Form
Ultrasonic, Rheological and Conductivity Study of the Interaction between Polyacrylic Acid and DTAB Micelles in Aqueous Medium
Recent Advancements in the Synthesis and Biological Applications of Naphthaldehyde Derived Schiff base Ligands and Transition Metal Complexes
Hydrotropy Driven Green Analytical Methods: A Sustainable Approach for Poorly Water-Soluble Drugs
The Carbazole Pharmacophore: Rational Design, Mechanistic Insights and Clinical Prospects for Novel Antimicrobial Agents
Greener Analytical Technique: A Step towards Sustainable Pharma

Tags


About Journal

Asian Journal of Research in Chemistry (AJRC) (ISSN: print-0974-4169, Online-0974-4150) is an international, peer-reviewed journal devoted to pure and applied chemistry. AJRC publishes Original Research Articles, Short Communications, Review Articles in all aspects of chemistry. Topics covered including the traditional areas of analytical, inorganic, organic, biochemistry, forensic, physical-theoretical chemistry as well as newer interdisciplinary areas such as agriculture, materials science, computational, medicine, spectroscopy, polymers, supramolecular, surface, chemical physics, biological, medicinal/ drugs, environmental and pharmaceutical chemistry.
The journal is published quarterly every year in last week of March, June, September and December. From January 2011, is monthly and shall be published every year in last week of Month.    
Read More  

Quick Links