To Investigate the Temperature effect on Thermodynamic Parameters of substituted Thiocarbamidophenol in 60% Ethanol Water Mixture.

 

S. O. Mohod, D. T. Tayade*

Department of Chemistry, Government Vidarbha Institute of Science and Humanities, Amravati 444 604, Maharashtra State, India.

*Corresponding Author E-mail: seemamohod7@gmail.com

The conductometric investigation of 2-chlorophenylthiocarbamidophenol (CTCP) or L₃ have been studied at different concentration at 60% ethanol-water mixture at different temperatures G,k,µ values are determined. The thermodynamic parameters ΔH, ΔG and ΔS for the ion pair formation determine from the value of ion association constant at constant temperature. This measurement revealed that solvent-solvent, solute-solvent and solute-solute interaction and the effects of various substituents.

 

 

 

INTRODUCTION:

Study on the transport properties of electrolytes indifferent solvent media is extremely important to obtain information regarding the solvation and association behavior of ions in solutions. The electrical conductivity of electrolytes in solvent mainly depends on the concentration of electrolytes and viscosity of the solvent. The application of salt is well understood from the study of ionic solvation. Conductometric and related studies of electrolytes in non-aqueous solvent have been done in relation to the application of these types of electrolytes in high energy battery and further making out of organic reaction mechanisms. Conductometric method is widely used because of its various advantages such as low cost, eco-friendly, less time consuming, proper thermodynamic calculation with different parameters and most important easy to operate^1-3.

 

Using conductometric method researchers can calculate all thermodynamic parameters for specific reaction and also investigate stability constant. By using conductometric method, basic research on thermodynamic studies like enthalpy, entropy, Gibb’s free energy can also be determined^4-5. Jaganraj et al⁶ investigated the study on sodium acetate and sodium benzoate in ethanol-water mixed solvent media conductometrically. The conductometric determination of formation constants of tris(2-pyridyl)methalyanine and titanium(III) in water-acetonitryl mixture by Rezayi et al⁷. Owayami et al⁸ studied thermodynamic of micellization of n-alkyltriphenylphosphonium bromide by conductometric technique. Fanta⁹ investigated surface and thermodynamic parameters of micellization of surfactants in binary mixture of 1, 2-ethanediol and 1, 2, 3-propanetriol with water. Farooqui et al¹⁰ investigated conductance of metal salt in binary solvent system at 25^oC in absence of and presence of three pharmaceutical drugs by conductometric method. Ali et al¹¹ studied the interaction of cetrimide with sodium dodecyl sulfate in aqueous medium conductometrically. Mansri A et al¹² investigated the conductometric study of the complex system polyelectrolyte/surfactant in aqueous solution. The present work is carried out for investigation of conductometric properties, thermodynamic behavior and walden product of 2-chlorophenylthiocarbamidophenol in 60% ethanol-water mixture at different temperature and different concentration.

 

EXPERIMENTAL SECTION:

In this research work all solutions are freshly prepared. AR grade chemical are used. The solutions 0.1M, 0.05M, 0.025M and 0.0125M of 2-chlorophenylthiocarbamidophenol were prepared. Thermostat was used to maintain the thermal equilibrium of drug solution. After thermal equilibrium the conductance of solution was measured.

 

RESULT AND DISCUSSION:

The solution of 0.1M was firstly prepared then after by using serial dilution method the solutions of 0.05M, 0.025M and 0.0125M were prepared in 60% ethanol-water mixture. The conductances of solutions were measured by using Conductivity Bridge at 298.15K and 303.15K. With the known literature method observed conductance (G), specific conductance (k) and molar conductance (µ) were determined. The result obtained was presented in Table-1 and Table-2.

 

TABLE. 1 - CONDUCTOMETRIC MEASUREMENTS AT DIFFERENT CONCENTRATIONS OF L₃ [CTCP]

 

With the known literature method, the specific constant (K_sp), log(K_sp) and thermodynamic parameters viz. change in free energy (ΔG), change in entropy(ΔS) and change in   enthalpy (ΔH) of [PTCP] at various molar concentration at different temperature (298.15K and 303.15K) which is shown in Table-2

 

TABLE. 2 - CONDUCTOMETRIC MEASUREMENTS AT DIFFERENT CONCENTRATIONS OF L₃[CTCP]

 

CONCLUSION:

Table-1 showed that the observed conductance (G), specific conductance (k) decreases and molar conductance (µ) were increases. The specific conductance (G) decreases and molar conductance (µ) increases along with decreasing molar concentrations with increase in temperatures. Table-2 specifies that when we going from molar concentration 0.1M to 0.125M concentration solutions the values K_sp, log K_sp, ΔH, ΔS decreases while ΔG increases with increase in temperatures. These parameters influence by structures and nature of synthesized compounds. The temperature, molar concentration and percentages composition directly affects the thermodynamic parameters. These parameters links with other like solute-solute, solute-solvent and solvent-solvents interactions. Internal geometry and inter and intra-hydrogen bonding also affects these parameters.

 

REFERENCES:

1.        Matsuura N, Umemoto K, Takeda Y, Sasaki A. “Formulation of stokes’ radii in DMF, DMSO and propylene carbonate with solvent structure cavity size as parameter.”Bull. Chem. Soc. Jpn., 48(8); 1975: 2253-2257.

2.        Lawrance GA. Introduction to coordination chemistry, A Wiley series of advance text books, ISSN939-5175, 2010.

3.        Pengju J, Guo Z. “Fluorescent detection of zinc in biological systems: recent development on the design of chemosensors and biosensors.” Chem Rev., 248(1-2); 2004: 205-229.

4.        Francis AC, Shrivastav PS. “Conductometric studies on cation-crown ether complexes: A review” Crit. Rev. Anal. Chem., 41(3); 2011:236-269.

5.        De Silva AP, Gunaratne HQN, Gunnlaugsson T, Huxley JM, Mchoy CP, Rademacher JT, Rice TE. “Signaling recognition events with fluorescent sensors and switches” Chem. Rev., 97(5); 1997: 1515-1566.

6.        Jaganraj S, Subha J, Sudarsan SB. Int. J. of Adv. Chem. Sci. and App., 2(4); 2014.

7.        Rezayi M, Kasim A, Ahmadzadeh S, Yusof NA, Najr A. “Conductometric determination of formation constants of tris(2-pyridyl)methylamine and titanium (III) in water acetonitryl mixture.”Int. J. Electrochem. Sci., 6; 2011:4378-4387.

8.        Owayami O, Lge J, Soriyan OO. “Thermodynamics of micellization of n-alkyltriphenylphosphonium bromides: a conductometric study.”Chem. Sci.  J., 25; 2011: 1-13.

9.        Fenta AD. “Surface and thermodynamic studies of micellization of surfactants in binary mixtures of 1, 2-ethanediol and 1, 2, 3-p “ropanetriol with water” Int. J. of Phy. Sci., 10(8); 2015: 276-288.

10.     Farooqui M, Shafique M, Asif S, Mukhtar S. “Study of conductance metal salts in binary solvent systems at 250C and in absence and in presence of three pharmaceutical drugs.”Int. J. of Adv. in Pharma. Sci., 2(2-3); 2011: 146-154.

11.     Ali A, Malik NA, Uzair S, Farooq U. “Conductometric study of the interaction of cetrimide with sodium dodecyl sulphate in aqueous medium”J. of Sol. Chem., 44(8); 2015: 1640-1654.

12.     Tennouga L, Medjahed K, Mansri A, Grassel B. “Conductometric study of the complex system polyelectrolyte/surfactant in aqueous solution” Res. On Chem. Inter., 39(6); 2013: 2527-2536.

 

 

Received on 17.03.2017         Modified on 25.03.2017

Accepted on 07.04.2017         © AJRC All right reserved