ISSN

0974-4150 (Online)
0974-4169 (Print)


Author(s): Parmesh Kumar Dwivedi, Kishu Tripathi, Mamta Mishra

Email(s): kishutripathi@rediffmail.com

DOI: Not Available

Address: Parmesh Kumar Dwivedi1, Kishu Tripathi2 and Mamta Mishra3
1Amity University, Lucknow
2Surya College of Pharmacy, Lucknow
3State Public Analytical Laboratory(FDA), Lucknow
*Corresponding Author

Published In:   Volume - 2,      Issue - 4,     Year - 2009


ABSTRACT:
Aminopyrimidine and its derivatives have a great biological importance .In last decades a number of compounds have been synthesized having aminopyrimidine moiety either fused with other ring system or its derivatives. These synthesized compounds show a lot of biological activity like anticancer, antimicrobial, antimalarial, antiviral and various other biological activities having importance in the treatment of diseases. Many reviews on pyrimidine are available but there is no collective information about aminopyrimidines for recent years. The purpose of present review is to provide exhaustive information about the aminopyrimidine as new target of drug synthesis.


Keywords:

Cite this article:
Parmesh Kumar Dwivedi, Kishu Tripathi, Mamta Mishra. The Aminopyrimidines-I. Asian J. Research Chem. 2(4):Oct.-Dec. 2009 page 360-364.

Cite(Electronic):
Parmesh Kumar Dwivedi, Kishu Tripathi, Mamta Mishra. The Aminopyrimidines-I. Asian J. Research Chem. 2(4):Oct.-Dec. 2009 page 360-364.   Available on: https://ajrconline.org/AbstractView.aspx?PID=2009-2-4-1


REFERENCES:

1.        Robins,R.K .In Heterocyclic Compounds Ed. Elderfield, R.C.,Wiley, New York,1967,pp 8.

2.        Ingram, V.M. In The Biosynthesis of Macromolecules Eds.Benjamin, W.A. Inc.,New  York,1965.

3.        Matner, H.G.; Clemson,H.C. Medicinal Chemistry ed. Burger,A., Wiley, New York, 3rd Edn.,1970,2,1365.

4.        Ruiz, J. C.; Beadle , J. R.; Aldern, K. A.; Keith, K. A.;Hartline, C.B.; Kern, E. R; Hostetler, K. Y; Antiviral Research (2007) 75 87–90

5.        Numazaki, K; Chiba ,S; Clinical and Diagnostic Virology, Volume 8, Issue 3, November 1997, Pages 169-181

6.        Xiong ,X; Smith, J. L.; Kim ,C; Huang,E.; Chen, M. S.;
Biochemical Pharmacology, Volume 51, Issue 11, 14 June 1996, Pages 1563-1567

7.        Hitchock ,M.J.M.; Lacy ,S.A.; Lindsey ,J.R.; Ker,E.R;.
Antiviral Research, Volume 26, Issue 3, March 1995, Page A358

8.        Evidence-Based Healthcare and Public health, Volume 9, Issue 1, February 2005, Pages 75-76

9.        Clercq, D.E.; Journal of Clinical Virology, Volume 30, Issue 2, June 2004, Pages 115-133

10.      Clercq, E.D.; Journal of Clinical Virology, Volume 22, Issue 1, August 2001, Pages 73-89

11.      Clercq ,E. D.; Il Farmaco, Volume 56, Issues 1-2, 1 March 2001, Pages 3-12

12.      Loomba,R.; Rowley, A. K.; Wesley, R.; Smith,K.G.; Liang, T. J.; Pucino, F.; Csako, G.; Clinical Gastroenterology and Hepatology, Volume 6, Issue 6, June 2008, Pages 696-700

13.      Lenci ,I.; Piccolo,P;. PaoloD. D.; Cerocchi, C.; Trinito,M.; Angelico,M.; Digestive and Liver Disease, Volume 40, Issue 5, May 2008, Pages A17-A18

14.      Abu-ata ,O.; Slim,J.; Perez,G.; Smith,S. M;.
Advances in Pharmacology, Volume 49, 2000, Pages 1-40

15.      Clercq,E.D,.Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, Volume 1587, Issues 2-3, 18 July 2002, Pages 258-275.

16.      Clercq,E.D., Il Farmaco, Volume 56, Issues 1-2, 1 March 2001, Pages 3-12

17.      Lipsky, J. J .The Lancet, Volume 341, Issue 8836, 2 January 1993, Pages 30-32.

18.      Bruce C., Köhne C.H., Audisio R.A.European Journal of Surgical Oncology (EJSO), Volume 33, Supplement 2, December 2007, Pages S84-S87

19.      Labianca ,R.; Milesi, L.; Mosconi, S.; Pessi, M.A.; Beretta, G.D.; Quadri, A.,Surgical Oncology, Volume 16, Supplement 1, December 2007, Pages 93-96

20.      Gramont ,A. , Tournigand, C.; André, T.; Larsen, A. K.; Louvet, C.,Seminars in Oncology, Volume 34, Supplement 1, April 2007, Pages S37-S40

21.      Guilhot F.; Gardembas, M.; Rousselot, P.; Tulliez, M.; Vigier, M.; Buzyn, A.; Rigal-Huguet, F.; Legros, L.; Michallet, M.; Berthou, C.; Najman, A.; Maloisel, F.; Mahon, F.; Facon ,T.; Berthaud, P.; Guilhot, J., and CML French Group Seminars in Hematology, Volume 40, Issue 2, Supplement 1, April 2003, Pages 92-97

22.      Gasparini ,M.; Rottoli, L; Massimino, M.; Gianni, M.C.; Ballerini, E.; Fossati-Bellani, F.; Ravagnani ,F.; Pupa, S.. European Journal of Cancer, Volume 29, Issue 5, 1993, Pages 692-698

23.      Thomas ,J.; Pauw, B.; Hagenbeek, A.; Somers, R.; Carde, P.; Tirelli, U.; Duez, N.   European Journal of Cancer, Volume 28, Issues 4-5, April-May 1992, Pages 857-859,

24.      Foon ,K. A.; Gale, R. P,.Blood Reviews, Volume 6, Issue 1, March 1992, Pages 15-25

25.      Vermorken, J. B.; Huinink,W. W. B., The Breast, Volume 5, Issue 4, August 1996, Pages 304-311

26.      Mader ,M.M.; Henry,J.R., Comprehensive Medicinal Chemistry II, 2007, Chapter 7.03, Pages 55-79

27.      Rider,B. J.,xPharm: The Comprehensive Pharmacology Reference, 2008, Pages 1-3

28.      Seminars in Hematology, Volume 40, Issue 2, Supplement 1, April 2003, Pages 15-20
Capdeville R.; Silberman, S.

29.      Capdeville ,R.; Silberman, S.; Dimitrijevic S..European Journal of Cancer, Volume 38, Supplement 5, September 2002, Pages S77-S82;

30.      Lipsky ,J. J.,The Lancet, Volume 341, Issue 8836, 2 January 1993, Pages 30-32

31.      McCombie ,S. C.Social Science and Medicine, Volume 43, Issue 6, September 1996, Pages 933-945

32.      BynumB The Lancet, Volume 371, Issue 9622, 26 April 2008-2 May 2008, Pages 1407-1408

33.      ShuteP. G.Transactions of the Royal Society of Tropical Medicine and Hygiene, Volume 64, Issue 2, 1970, Pages 210-216

34.      Harrison ,T S;, Brouwer, A. E Medicine, Volume 33, Issue 5, 1 May 2005, Pages 116-119

35.      MerkH. F., Mukhtar ,H Clinics in Dermatology, Volume 7, Issue 3, July-September 1989, Pages 121-127.

36.      Burchall,J.J.;J.Antimicrob.Chemother.1979,5(suppl.B.),3.

37.      Hitchings, G.H.;Elion, G.B.;Vander Werrf, H.;Falco,E.A.J.Biol.Chem.,1948,174,765.

38.      Burcall, J.J.;Hitching, G.H.; Mol.Pharmacol.1965,1,126.

39.      Roth, B.;Falco,E.A.; Hitching, G.H.;Bishby, S.R.M.J. Med.Pharm.Chem;1962,5,1103.

40.      Weinstein, L.’The Pharmacological Basis of Therapeutics’,ed.Goodman,L.S.;Gillman,A.Macmillan,New York, 5th Edn.,1975,102.

41.      Fox,C.L.Jr.;Modak,S.M.Antimicrob.AgentsChemother.1974,5,582

42.      Myint ,H.Y.;, Tipmanee, P.;, Nosten, F; Day, N. P. J., Pukrittayakamee S.;, Looareesuwan, S;, White, N. J..Transactions of the Royal Society of Tropical Medicine and Hygiene, Volume 98, Issue 2, February 2004, Pages 73-81

43.      Govere ,J. M. Evidence-based Healthcare, Volume 6, Issue 2, June 2002, Pages 79-80

44.      Aleem,G.; Yibin, Z.; Guire, M.; John J.; Kisliuk, R. L.;    Journal of Medicinal Chemistry  (2002),  45(23),  5173-5181

45.      Gangjee, A; Shi, J; Queener, S. F;.Journal of Medicinal Chemistry  (1997),  40(12),  1930-1936. 

46.      Donkor, I.O.; Devraj, R; Queener, S. F.; Barrows, L. R.; Gangjee, A;.    Journal of Heterocyclic Chemistry  (1996),  33(6),  1653-1661

47.      Piper, J.R.; Montgomery, J. A.  PCT Int. Appl.  (1993),     41 pp.  CODEN: PIXXD2  WO  9313102  A1  19930708  .    Application: WO  91-US9743  19911230.  Priority: .  CAN 119:271198    AN 1993:671198  

48.      Phiasivongsa, P.; Redkar, S.; Gamage, S.; Brooke, D.; Denny, W.; Bearss, D. J.; Vankayalapati, H. PCT Int. Appl.  (2008),     169pp., which.  CODEN: PIXXD2  WO  2008046085  A2  20080417  .    Application: WO  2007-US81321  20071012.  Priority: US  2006-921502  20061012; US  2007-911850  20070413.  CAN 148:471880    AN 2008:479638   

49.      Mao, Z.; Liu, Z.; Zhu, G.  (2007),     16pp.  CODEN: CNXXEV  CN  1986545  A  20070627  .    Application: CN  1014-8232  20061228.  AN 2007:706211   

50.      Song., Y.; Hou, Y.; Gupta, S.; Reed, A. D.; Ghosh, D.  (USA).    U.S. Pat. Appl. Publ.  (2007),     20pp.  CODEN: USXXCO  US  2007082920  A1   Application: US  2005-244614  20051006.  Priority: .  CAN 146:395245    AN 2007:408008  

51.      Donkor, I.O.; Klein, C. L.; Liang, Li; Zhu, N.; Bradley, E.; Clark, A.M.      Journal of Pharmaceutical Sciences  (1995),  84(5),  661-4. 

52.      Kovalenko, S.I.;Mazur,I.A.;sinyak,R.S.;Brazhko,O.A.;Andruschchenko,A.V.;Niktin, V.O.; Karpenko, O.V. Farmatsevtichnii Zhurnal (Kiev),2001,3,55

53.      Abdou,N.A;Youssef,K.M.;Kandeel,M.M.;Soliman,L.N.Bull.Fac.Pharm.,1993,31,361.

54.      Gangjee,A.;Adair,O.;Queener,S.F.Bioorg.Med.Chem.,2001,9,2929.

55.      Joshi, A. A.; Narkhede, S. S.; Viswanathan, C. L.    .    Bioorganic and Medicinal Chemistry Letters  (2005),  15(1),  73-76. 

56.      Donkor, I.O.; Devraj, R.; Queener, S.F.; Barrows, L.R.; Gangjee, A.    Journal of Heterocyclic Chemistry  (1996),  33(6),  1653-1661

Recomonded Articles:

Author(s): Parmesh Kumar Dwivedi, Kishu Tripathi, Mamta Mishra

DOI:         Access: Open Access Read More

Author(s): Parmesh Kumar Dwivedi, Kishu Tripathi, Mamta Mishra

DOI:         Access: Open Access Read More

Author(s): Sarfraz Alam, Garima Avasthi

DOI:         Access: Open Access Read More

Asian Journal of Research in Chemistry (AJRC) is an international, peer-reviewed journal devoted to pure and applied chemistry..... Read more >>>

RNI: Not Available                     
DOI: 10.5958/0974-4150 


Recent Articles




Tags