Author(s):
Shivani Koul, Shyama, Reetesh Ramnani, Anupam Srivastava
Email(s):
Shivani.koul001@gmail.com
DOI:
10.52711/0974-4150.2025.00040 
Address:
Shivani Koul1, Shyama2, Reetesh Ramnani3, Anupam Srivastava4
1PhD Scholar, Department of Rasa Shastra Evum Bhaishajya Kalpana, National Institute of Ayurveda Deemed University, Amer Rd, Jaipur, Rajasthan.
2PhD Scholar, Department of Rasa Shastra, Evum Bhaishajya Kalpana, National Institute of Ayurveda Deemed University, Amer Rd, Jaipur, Rajasthan.
3Assistant Professor, Department of Rasa Shastra Evum Bhaishajya Kalpana, National Institute of Ayurveda Deemed University, Amer Rd, Jaipur, Rajasthan.
4Head of Department, Department of Rasa Shastra Evum Bhaishajya Kalpana, National Institute of Ayurveda Deemed University, Amer Rd, Jaipur, Rajasthan.
*Corresponding Author
Published In:
Volume - 18,
Issue - 4,
Year - 2025
ABSTRACT:
Introduction: The term Rasa Shastra translates to the "Science of Mercury," with Rasa being a synonym for mercury itself. This specialized branch of Ayurveda primarily deals with the processing and therapeutic application of substances derived from metals, minerals, and herbo-mineral origins. It encompasses a wide array of substances collectively known as Rasa Dravyas, which include Rasa (mercury), Maharasa, Uparasa, Sadharana Rasa, Dhatu, Upadhatu, Ratna, Upratna, Visha, and Upavisha. Formulations prepared using these ingredients—excluding purely herbal preparations—are classified as Rasaushadhis (herbo-metallic or metallic medicines). These formulations are valued in Ayurveda for their potent therapeutic effects, which include rapid action, minimal dosage requirement, and broad-spectrum efficacy regardless of a person’s constitution (Prakriti). Besides treating ailments, Rasaushadhis are also recognized for their Rasayana (rejuvenative) properties, contributing to delayed aging, enhanced vitality, improved immunity, and strengthened body tissues. Materials and Methods: A range of classical Ayurvedic texts and contemporary scholarly resources were consulted to compile information related to Rasaushadhis. This study aims to highlight the significance of Rasa Shastra as a distinct Ayurvedic discipline, its historical development, and categorization of Rasa Dravyas including Rasa, Uparasa, Maharasa, Sadharana Rasa, Dhatu, Upadhatu, Ratna, Upratna, Visha, and Upavisha. The classification of Rasaushadhis into mercurial and non-mercurial groups is discussed, with particular focus on the role of mercury and its compounds like mercuric sulphide. The paper also outlines the potential toxicity risks of improperly prepared Rasaushadhis, essential precautions during administration, and emphasizes the necessity of purification (Shodhana) and proper pharmaceutical processing. Additionally, both traditional Ayurvedic and modern scientific analytical techniques—such as organoleptic evaluation, physicochemical testing, and advanced instrumentation—are briefly reviewed to ensure the safety and efficacy of these formulations. Conclusion: Rasaushadhis exhibit significant therapeutic benefits across a broad range of health conditions. They are widely appreciated for their rapid onset of action, low dosage, palatability, ease of administration, and extended shelf life. However, their safe and effective use hinges on meticulous preparation involving proper purification and processing, alongside thorough evaluation through classical and modern analytical methods. Adherence to appropriate dosage, timing, dietary restrictions (Pathya), and contraindications (Apathya) is crucial to harness their full therapeutic potential while avoiding adverse effects.
Cite this article:
Shivani Koul, Shyama, Reetesh Ramnani, Anupam Srivastava. The Role and Significance of Rasa-Aushadhis in Ayurvedic Pharmacology: A Comprehensive Overview. Asian Journal of Research in Chemistry.2025; 18(4):255-4. doi: 10.52711/0974-4150.2025.00040
Cite(Electronic):
Shivani Koul, Shyama, Reetesh Ramnani, Anupam Srivastava. The Role and Significance of Rasa-Aushadhis in Ayurvedic Pharmacology: A Comprehensive Overview. Asian Journal of Research in Chemistry.2025; 18(4):255-4. doi: 10.52711/0974-4150.2025.00040 Available on: https://ajrconline.org/AbstractView.aspx?PID=2025-18-4-9
REFERENCE:
1. Caraka Samhita with Aayurved Dipika commentary by Cakrapaani edited by Vaidya Jadavaji Trikamji Acharya (1984). Sutra Sthaana 26/12. Choukhmba Sanskrita Sansthan, Varanasi (India).
2. Caraka Samhita with Aayurved Dipika commentary by Cakrapaani edited by Vaidya Jadavaji Trikamji Acharya (1984). Sutra Sthaana 1/68. Choukhmba Sanskrita Sansthan, Varanasi (India).
3. Sushruta Samhitaa with Nibandh Sangraha commentary by Dalhana, edited by Jadavaji Trikamaji Aacaarya, (1992). 5th edition. Sutra Sthana- 1/32. Choukhamba Orientalia, Varanasi (India).
4. Vaagbhata, Rasaratnasamuccaya, fifth edition (1976). Chowkhamba Sanskrit Series Office, Varanasi (India).
5. Anonymous, (2004). “(Raseshvara darshan, quoted in Maadhvaacaarya, ‘Sarvadarshana Samgriha’ Dr. Umashankar Sharma ‘Rishi’- Ed). Chowkhambha Vidya Bhavana, Varanasi, 221001, (India), page- 329.
6. Vaagbhata, Rasaratnasamuccaya, fifth edition (1976), Chowkhamba Sanskrit Series Office, Varanasi (India), page-137.
7. Gautam.S et.al., Rasaaushadi (Metallo-medicine)-Pharmaceutical factors for safe and effective medicine, International Ayurvedic Medical Journal, ISSN:2320 5091.
8. Dr. Sidhinandan Mishra, A text book of Ayurvedic RasaShastra. Chaukhambha Orientalia Varanasi, Reprint 2007; p.12.
9. Shastri Pd. Kashinath, Rasa tarangini of Sadanand Sharma, Motilalbanarasi Publication. Delhi.2nd Edition 2012; p.99-114.
10. Dr.Ramachandra Reddy. Text book of Rasashastra, Chaukhambha Sanskrit Bhawan, Varanasi, Second Edition 2010; p.22.
11. Savrikar, S., & Ravishankar, B. (2011). Introduction to ‘Rasashaastra’-the iatrochemistry of Ayurveda. African Journal of Traditional, Complementary and Alternative Medicines, 8(5S).
12. Mukheria, P. K. (n.d.). Pocket book of Ayurvedic medicine reckoner. Jaypee Brothers Medical Publishers.
13. Joshi, N., Dash, M. K., & Panda, P. (2018). Critical review on the concept of Kajjali: The boon of Ayurvedic Herbomineral preparations (Rasaushadhi). Int J Green Pharm, 11, 112-5.